Department of Urology, National Academy of Medical Sciences, Bir Hospital, Kathmandu, Nepal.
Published: August 2019
AI Article Synopsis
Article Abstract
Background: Urinary stone disease has high prevalence in our belt. The end stage complication of this disease turns out to be a non-functioning kidney, which in fact could be prevented by means of appropriate treatment and follow up.
Methods: This is retrospective study of the nephrectomy cases of last 8 years retrieved from the hospital database. Variables like age, sex, indications for nephrectomy, modalities of nephrectomy and morbidities among the primary and recurrent disease were taken into consideration. Analysis were done using Microsoft Excel 2016.
Results: Five hundred and twenty-nine nephrectomies were performed in last 8 years at our hospital. Female were more prone for nephrectomies. Age at third and fourth decade were most to be affected. Ninety percentage of nephrectomies were done for benign causes, 65% for the stone disease. The recurrent renal stone disease without any past surgical interventions were more prone to undergo nephrectomies. The conventional open technique of nephrectomy has largely been replaced by laparoscopic means in recent years.
Conclusions: The main contributor for nephrectomy in our context is urinary stone disease, which is considered to be the preventable factor Keywords: Nephrectomy; renal stone; urinary stone disease.
Objective: To analyze the nutritional content of Shanxi's main vegetables and fruits.
Methods: According to the national food safety standards, the nutritional content of 25 vegetables and 38 fruits produced in Shanxi Province from 2018 to 2022 were evaluated for their energy, protein, fat, carbohydrates, vitamins, and minerals.
Results: The contents of energy and carbohydrate of the vegetable samples from high to low were allium, solanum and tender stems, leaves and cauliflower, respectively, The contents of protein from high to low were allium, tender stems, leaves, cauliflower and solanum; The contents of carotene, vitamin B_1, vitamin B_2 and vitamin E in solanaceous vegetables were the highest, and the contents of vitamin C were the tender stems, leaves and cauliflower vegetables.
The gut microbiota (GM) can affect the immune system, which can lead to a variety of diseases, as confirmed by many studies. However, the exact mechanism by which GM affects kidney stone incidence through the immune system remains unclear. This study used a two-step, two-sample Mendelian randomization (MR) analysis by inverse variance weighting (IVW) method as well as Bayesian weighting (BWMR) to find out how the gut microbiota and inflammatory cytokines contribute to kidney stones, followed by a mediated MR analysis to exploreHow inflammatory cytokines are involved in the connection with the gut microbiota and kidney stones.
Biliary sepsis, characterized by contamination and infection of the biliary tract, poses a serious medical issue with detrimental effects on the patients. While cholecystectomy is the usual treatment for symptomatic gallstones, the most desirable management approach for biliary sepsis remains debated, prompting a scientific evaluation of the long-term effects of cholecystectomy. To compare the long-term outcomes of biliary sepsis in patients undergoing cholecystectomy versus conservative management (CM), this study will systematically review the existing literature to clarify differences in recurrence rates, complication rates, and overall survival.
Background: Hypertension (HTN) is a major global public health concern. This study aims to identify gender differences to inform more effective prevention strategies and targeted management approaches.
Methods: This prospective cohort study included 7,710 participants aged 40 to 70 years, with a mean follow-up duration of 5.
The primary objective of urolithiasis therapy is complete stone removal and highest stone-clearance rates possible to minimize recurrence. A novel approach that employs a magnetic suspension and a magnetic probe for the passive collection and removal of small residual fragments was developed. This study assessed the feasibility of this system in porcine models.
