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http://dx.doi.org/10.1212/NXI.0000000000000589 | DOI Listing |
AJNR Am J Neuroradiol
January 2025
From the Department of Radiology (GMC, MM, YN, BJE), Department of Quantitative Health Sciences (PAD, MLK, JEEP), Department of Neurology (CBM, JAS, MWR, FSG, HKP, DHL, WOT), Department of Neurosurgery (TCB), Department of Laboratory Medicine and Pathology (RBJ), and Center for Multiple Sclerosis and Autoimmune Neurology (WOT), Mayo Clinic, Rochester, MN, USA; Dell Medical School (MFE), University of Texas, Austin, TX, USA.
Background And Purpose: Diagnosis of tumefactive demyelination can be challenging. The diagnosis of indeterminate brain lesions on MRI often requires tissue confirmation via brain biopsy. Noninvasive methods for accurate diagnosis of tumor and non-tumor etiologies allows for tailored therapy, optimal tumor control, and a reduced risk of iatrogenic morbidity and mortality.
View Article and Find Full Text PDFMult Scler J Exp Transl Clin
December 2024
Department of Neurology, Tokyo Women's Medical University, Tokyo, Japan.
Background: Few studies have examined B cells among patients with anti-myelin oligodendrocyte glycoprotein (MOG) antibody-associated disease (MOGAD), including brain pathology.
Objective: To describe cases of tumefactive MOGAD with B-cell dominant central nervous system (CNS) infiltration.
Methods: In this study, we reviewed three cases with clinical and brain histopathological features with tumefactive MOGAD.
BMC Med Imaging
November 2024
School of Medicine, Southeast University, Nanjing, China.
Objective: Differentiating intramedullary spinal cord tumor (IMSCT) from spinal cord tumefactive demyelinating lesion (scTDL) remains challenging with standard diagnostic approaches. This study aims to develop and evaluate the effectiveness of a magnetic resonance imaging (MRI)-based radiomics model for distinguishing scTDL from IMSCT before treatment initiation.
Methods: A total of 75 patients were analyzed in this retrospective study, comprising 55 with IMSCT and 20 with scTDL.
Mult Scler Relat Disord
December 2024
Faculty of Medicine, University of Belgrade, Serbia; Neurology Clinic, University Clinical Center of Serbia, Serbia. Electronic address:
Cureus
August 2024
Cardiology, MGM Healthcare, Chennai, IND.
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