Epitope-based vaccine as a universal vaccination strategy against infection: A mini-review.

J Adv Vet Anim Res

Department of Medical Microbiology & Parasitology, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia.

Published: June 2019

Despite the significant progress in the recent efforts toward developing an effective vaccine against toxoplasmosis, the search for new protective vaccination strategy still remains a challenge and elusive goal because it becomes the appropriate way to prevent the disease. Various experimental approaches in the past few years showed that developing a potential vaccine against the disease can be achievable. The combination of multi-epitopes expressing different stages of the parasite life cycle has become an optimal strategy for acquiring a potent, safe, and effective vaccine. Epitope-based vaccines have gained attention as alternative vaccine candidates due to their ability of inducing protective immune responses. This mini-review highlights the current status and the prospects of vaccine development along with the application of epitope-based vaccine in the future parasite immunization as a novel under development and evaluation strategy.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702889PMC
http://dx.doi.org/10.5455/javar.2019.f329DOI Listing

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