Paratesticular rhabdomyosarcoma is a rare tumor. Treatment is based on multimodal therapy as well as on surgery, chemotherapy and radiotherapy. This study and literature review highlight the diagnostic and therapeutic approaches to treat paratesticular rhabdomyosarcoma.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690064 | PMC |
| http://dx.doi.org/10.11604/pamj.2019.33.55.17269 | DOI Listing |
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Long-Term Urinary and Sexual Outcomes in Pediatric Genitourinary Rhabdomyosarcoma Survivors: A Qualitative Study.
J Urol
December 2024
Department of Urology, Boston Children's Hospital, Boston, Massachusetts.
Purpose: Genitourinary rhabdomyosarcoma (GU-RMS) often requires multimodal therapy treatment including radiation, chemotherapy, and radical surgery for disease control. The long-term effects of the disease and associated treatments are unclear. We sought to investigate the long-term genitourinary quality of life for adult survivors of pediatric GU-RMS.
View Article and Find Full Text PDFAnalysis of Genitourinary Rhabdomyosarcoma in Phase 3 clinical trials.
World J Urol
December 2024
Department of Urology, University of Rochester Medical Center, 601 Elmwood Avenue, Box 668, Rochester, NY, 14642, USA.
Purpose: Pediatric Rhabdomyosarcoma (RMS) is a morbid and often lethal condition characterized by a paucity of clinical data. Beyond a detailed risk categorization system, it is unclear if genitourinary (GU) sites (bladder/prostate, paratesticular, female organs) have outcomes distinct from non-GU sites. This study pools primary data from phase-3 clinical trials involving pediatric RMS to evaluate this question.
View Article and Find Full Text PDFAlveolar Paratesticular Rhabdomyosarcoma in an Adult Patient With PAX3-FOXO1 Fusion and Unfavorable Evolution.
Cureus
October 2024
Oncology, Pontifícia Universidade Católica Do Rio Grande Do Sul, Porto Alegre, BRA.
Rhabdomyosarcomas, malignant mesenchymal tumors of skeletal striated muscle tissue cells, are usually rare in adults. However, when they occur in this population, the prognosis is usually poor, especially if the condition is associated with molecular factors such as the PAX3-FOXO1 fusion. Here, We report a case of paratesticular alveolar rhabdomyosarcoma in an adult patient who initially complained of increased scrotal volume for two years and presented with a PAX3-FOXO1 fusion.
View Article and Find Full Text PDFHow Many Lymph Nodes are Enough in Paratesticular Rhabdomyosarcoma?
J Pediatr Surg
October 2024
Department of Urology, Division of Pediatric Urology, University of Kentucky, Lexington, KY, USA. Electronic address:
Background: Treatment strategies for paratesticular rhabdomyosarcoma (PT RMS) are based on stage, which requires accurate lymph node (LN) evaluation. Previous methodology for determining quantity of LN for negative nodal status is based on LN positivity rates, without accounting for the relationship between LNs or amongst patients. This study aims to quantify the chance of missing involved LNs based on LN yield (LNY) using a previously established methodology in comparison to current recommendations.
View Article and Find Full Text PDFRole of Fine Needle Aspiration Cytology in Paratesticular Neoplasms-A Case Reports-Based Systematic Review.
Diagn Cytopathol
December 2024
Department of Pathology and Lab Medicine, All India Institute of Medical Sciences, Bibinagar, Telangana, India.
Introduction: The cytology features of neoplastic paratesticular lesions are mostly documented as case reports. Thus, we conducted a case report-based literature review to identify the characteristics of paratesticular neoplasms and tried to determine the significance of FNAC in these tumors.
Methods And Materials: The studies were searched using PubMed and Scopus.
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