[Evolutive posterior forms of persistent fetal vasculature bilateral at Gao regional hospital].

Pan Afr Med J

Hôpital Hangadoumbo Moulaye Touré de Gao, Gao, Mali.

Published: September 2019

The persistence of fetal vasculature (PFV) is an abnormal resorption in hyaloid vascular system. We report the case of a 2-year old child with evolutionary posterior form of bilateral vasculature presenting with leukocoria in the right eye. Clinical examination showed bilateral leukocoria, exotropia in the right eye and an exotropia in the left eye. Fundus examination of the right eye showed fibrovascular retinal band stretched to the ora serrata associated with total retinal detachment and peripheral pigment changes. Fundus examination of the left eye showed fibrovascular retinal band stretched from the papilla to the ora serrata, associated with partial inferior, anterior temporal detachment and peripheral pigment changes.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691294PMC
http://dx.doi.org/10.11604/pamj.2018.31.215.16513DOI Listing

Publication Analysis

Top Keywords

fetal vasculature
8
left eye
8
fundus examination
8
eye fibrovascular
8
fibrovascular retinal
8
retinal band
8
band stretched
8
ora serrata
8
serrata associated
8
detachment peripheral
8

Similar Publications

Antagonisation of Prokineticin Receptor-2 Attenuates Preeclampsia Symptoms.

J Cell Mol Med

January 2025

Interdisciplinary Research Institute of Grenoble, IRIG-Biosanté, University Grenoble Alpes, INSERM, CEA, UMR 1292, Grenoble, France.

Preeclampsia (PE) is the most threatening pathology of human pregnancy. Placenta from PE patients releases harmful factors that contribute to the exacerbation of the disease. Among these factors is the prokineticin1 (PROK1) and its receptor, PROKR2 that we identified as a mediators of PE.

View Article and Find Full Text PDF

The spatial zonation of the murine placental vasculature is specified by epigenetic mechanisms.

Dev Cell

January 2025

Division of Vascular Oncology and Metastasis, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany; European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, 68167 Mannheim, Germany. Electronic address:

The labyrinthian fetoplacental capillary network is vital for proper nourishment of the developing embryo. Dysfunction of the maternal-fetal circulation is a primary cause of placental insufficiency. Here, we show that the spatial zonation of the murine placental labyrinth vasculature is controlled by flow-regulated epigenetic mechanisms.

View Article and Find Full Text PDF

Surgical Parameters and Prognostic Factors in Persistent Fetal Vasculature: Insights from a Retrospective Cohort Study.

Ophthalmol Ther

January 2025

Pediatric Ophthalmology and Strabismus Division, King Khaled Eye Specialist Hospital, Al Urubah Branche Rd., West Building 2nd Floor, 11462, Riyadh, Saudi Arabia.

Introduction: Persistent fetal vasculature (PFV) is a congenital anomaly associated with significant surgical challenges, including a high risk of postoperative retinal detachment (RD). This study aimed to evaluate the impact of surgical approach and axial length (AL) on RD risk and visual outcomes in pediatric PFV management.

Methods: A retrospective cohort study was conducted involving 76 eyes of 74 patients who underwent cataract surgery for PFV between 2014 and 2022.

View Article and Find Full Text PDF

The global issue of aging populations has become increasingly prominent, thus the research and development for anti-aging therapies to assure longevity as well as to ameliorate age-related complications is put high on the agenda. The young humoral milieu has been substantiated to impart youthful characteristics to aged cells or organs. Extracellular vesicles (EVs) are a heterogeneous group of cell-derived membrane-limited structures that serve as couriers of proteins and genetic material to regulate intercellular communication.

View Article and Find Full Text PDF

Background: Paternal preconception alcohol exposure affects fetal development; however, it is largely unknown about the influences on offspring vasculature and mechanisms.

Methods: Offspring born form paternal rats treated with alcohol or water before pregnant was raised until 3 months of age. Vessel tone of mesenteric arteries was detected using myograph system; whole-cell calcium channel current in smooth muscle cells was tested using patch-clamp; molecule expressions were detected with real-time PCR, western blotting, and Dihydroethidium (DHE); DNA methylations were determined using targeted bisulfate sequencing assay.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!