Deployment and performance of model-based dose calculation algorithm in Ir shielded cylinder brachytherapy.

Purpose: The purpose of the study was to integrate model-based dose calculation algorithm (MBDCA) and 3-D planning into our institutional capabilities for clinical cases with inherent heterogeneities, namely shielded cylinder cases, which were previously performed using templates.

Methods And Materials: AcurosBV (Varian Medical Systems) was selected as MBDCA, and we compared results against the American Association of Physicists in Medicine working group (WG) reference Test Case #4, which contains a 36-mm-diameter 180-degree shielded cylinder. The last five clinically used template plans, as generated with ABACUS (Varian Medical Systems), were compared against MBDCA results. Clinical plans used 20-, 23-, and 26-mm-diameter cylinders, prescribed from 5 to 7 Gy, 50- to 110-mm active length, 7 to 21 dwell positions, with 5- or 10-mm spacing.

Results: Compared with the WG reference plan, AcurosBV produced excellent agreement, within 1% at reference points. Larger deviations arose only within the applicator itself. Historical plans generated using ABACUS had higher point dose than AcurosBV by 3-4% or 2-3% using transport within medium at prescription points, with dose to medium or water, respectively.

Conclusions: To verify the accuracy of our MBDCA algorithm, we benchmarked against the WG data set available for shielded cylinders. We discovered a 3-4% difference in dose from our established historical templates, which is easily outweighed by daily positioning uncertainties. Dose distributions from MBDCA were used to assess and validate existing historical templates.