Visual querying is essential for interactively exploring massive trajectory data. However, the data uncertainty imposes profound challenges to fulfill advanced analytics requirements. On the one hand, many underlying data does not contain accurate geographic coordinates, e.g., positions of a mobile phone only refer to the regions (i.e., mobile cell stations) in which it resides, instead of accurate GPS coordinates. On the other hand, domain experts and general users prefer a natural way, such as using a natural language sentence, to access and analyze massive movement data. In this paper, we propose a visual analytics approach that can extract spatial-temporal constraints from a textual sentence and support an effective query method over uncertain mobile trajectory data. It is built up on encoding massive, spatially uncertain trajectories by the semantic information of the POls and regions covered by them, and then storing the trajectory documents in text database with an effective indexing scheme. The visual interface facilitates query condition specification, situation-aware visualization, and semantic exploration of large trajectory data. Usage scenarios on real-world human mobility datasets demonstrate the effectiveness of our approach.
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http://dx.doi.org/10.1109/TVCG.2019.2934671 | DOI Listing |
Front Biosci (Landmark Ed)
November 2024
Department of Hematology, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, 317000 Taizhou, Zhejiang, China.
In this comprehensive review, we delve into the transformative role of artificial intelligence (AI) in refining the application of multi-omics and spatial multi-omics within the realm of diffuse large B-cell lymphoma (DLBCL) research. We scrutinized the current landscape of multi-omics and spatial multi-omics technologies, accentuating their combined potential with AI to provide unparalleled insights into the molecular intricacies and spatial heterogeneity inherent to DLBCL. Despite current progress, we acknowledge the hurdles that impede the full utilization of these technologies, such as the integration and sophisticated analysis of complex datasets, the necessity for standardized protocols, the reproducibility of findings, and the interpretation of their biological significance.
View Article and Find Full Text PDFJ Inflamm Res
December 2024
Department of Dermatology, China-Japan Friendship Hospital, National Center for Integrative Medicine, Beijing, 100029, People's Republic of China.
Background: Psoriasis represents a persistent, immune-driven inflammatory condition affecting the skin, characterized by a lack of well-established biologic treatments without adverse events. Consequently, the identification of novel targets and therapeutic agents remains a pressing priority in the field of psoriasis research.
Methods: We collected single-cell RNA sequencing (scRNA-seq) datasets and inferred T cell differentiation trajectories through pseudotime analysis.
Can J Kidney Health Dis
December 2024
Division of Nephrology, Department of Medicine, Centre Hospitalier de l'Université de Montréal, QC, Canada.
Purpose: Highly sensitized patients (HSPs) with kidney failure have limited access to kidney transplantation and poorer post-transplant outcomes. Prioritizing HSPs in kidney allocation systems and expanding the pool of deceased donors available to them has helped to reduce their wait times for transplant and enhanced post-transplant outcomes. The Canadian HSP Program was established by Canadian Blood Services in collaboration with provincial organ donation and transplantation programs throughout the country to increase transplant opportunities for transplant candidates needing very specific matches from deceased kidney donors.
View Article and Find Full Text PDFNetw Neurosci
December 2024
Department of Psychology, University of Illinois Urbana-Champaign, Champaign, IL, USA.
Time-varying changes in whole-brain connectivity patterns, or connectome state dynamics, are a prominent feature of brain activity with broad functional implications. While infraslow (<0.1 Hz) connectome dynamics have been extensively studied with fMRI, rapid dynamics highly relevant for cognition are poorly understood.
View Article and Find Full Text PDFNetw Neurosci
December 2024
Coordinated Science Laboratory, University of Illinois, Urbana-Champaign, Urbana, USA.
A fine-grained understanding of dynamics in cortical networks is crucial to unpacking brain function. Resting-state functional magnetic resonance imaging (fMRI) gives rise to time series recordings of the activity of different brain regions, which are aperiodic and lack a base frequency. Cyclicity analysis, a novel technique robust under time reparametrizations, is effective in recovering the temporal ordering of such time series, collectively considered components of a multidimensional trajectory.
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