Energy coupling in ABC exporters.

Res Microbiol

Department of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1PD, UK.

Published: January 2020

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Article Abstract

Multidrug transporters are important and interesting molecular machines that extrude a wide variety of cytotoxic drugs from target cells. This review summarizes novel insights in the energetics and mechanisms of bacterial ATP-binding cassette multidrug transporters as well as recent advances connecting multidrug transport to ion and lipid translocation processes in other membrane proteins.

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http://dx.doi.org/10.1016/j.resmic.2019.08.003DOI Listing

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