Multidrug transporters are important and interesting molecular machines that extrude a wide variety of cytotoxic drugs from target cells. This review summarizes novel insights in the energetics and mechanisms of bacterial ATP-binding cassette multidrug transporters as well as recent advances connecting multidrug transport to ion and lipid translocation processes in other membrane proteins.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.resmic.2019.08.003 | DOI Listing |
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!