Talaromyces marneffei and other Talaromyces species can cause opportunistic invasive fungal infections. We characterized clinical Talaromyces isolates from patients in California, USA, a non-Talaromyces-endemic area, by a multiphasic approach, including multigene phylogeny, matrix-assisted laser desorption/ionization time-of-flight mass spectrometry, and phenotypic methods. We identified 10 potentially pathogenic Talaromyces isolates, 2 T. marneffei.
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| http://dx.doi.org/10.3201/eid2509.190380 | DOI Listing |
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Article Synopsis
- - High levels of antibodies to interferon-gamma (IFN-γ) are linked to infections from intracellular pathogens, especially non-tuberculous mycobacteria (NTM) and tuberculosis (MTB).
- - The case study discusses a non-immunosuppressed patient who had both MTB infection and complications from NTM, which led to a severe condition called secondary hemophagocytic syndrome.
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