Tools to detect human norovirus infectivity have been lacking. Using human intestinal enteroid cultures inoculated with GII.Pe-GII.4 Sydney-infected fecal samples, we determined that a real-time reverse transcription PCR cycle threshold cutoff of 30 may indicate infectious norovirus. This finding could be used to help guide infection control.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711227PMC
http://dx.doi.org/10.3201/eid2509.190205DOI Listing

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