Tucson, Arizona, USA, is a highly coccidioidomycosis-endemic area. We conducted a retrospective review of 815 patients in Tucson over 2.7 years. Of 276 patients with coccidioidomycosis, 246 had a delay in diagnosis; median delay was 23 days. Diagnosis delay was associated with coccidioidomycosis-related costs totaling $589,053 and included extensive antibacterial drug use.
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http://dx.doi.org/10.3201/eid2509.190023 | DOI Listing |
Sensors (Basel)
December 2024
Department of Mining and Geological Engineering, University of Arizona, Tucson, AZ 8572, USA.
Mining is a critical industry that provides essential minerals and resources for modern society. Despite its benefits, the industry is also recognized as one of the most dangerous occupations, with geotechnical hazards being a primary concern. This study introduces the hazard recognition in underground mines application (HUMApp), a mobile application developed to enhance safety within underground mines by efficiently identifying geotechnical hazards, specifically focusing on roof falls.
View Article and Find Full Text PDFPharmaceutics
December 2024
Laboratory for Fetal and Regenerative Biology, Department of Surgery, University of Arizona Tucson College of Medicine, Banner Children's at Diamond Children's Medical Center, 1656 E Mabel St, Rm 230, Tucson, AZ 85721, USA.
Dysregulated inflammation and oxidative stress are strongly implicated in the pathogenesis of inflammatory bowel disease. We have developed a novel therapeutic that targets inflammation and oxidative stress. It is comprised of microRNA-146a (miR146a)-loaded cerium oxide nanoparticles (CNPs) (CNP-miR146a).
View Article and Find Full Text PDFMicroorganisms
December 2024
Department of Environmental Science, University of Arizona, Tucson, AZ 85719, USA.
Resuspended particles from human activities can contribute to pathogen exposure via airborne fomite contamination in built environments. Studies investigating the dissemination of resuspended viruses are limited. The goal of this study was to explore viral dissemination after aerosolized resuspension via human activities on indoor flooring.
View Article and Find Full Text PDFMicroorganisms
December 2024
Department of Animal and Aquatic Sciences, Faculty of Agriculture, Chiang Mai University, Chiang Mai 50200, Thailand.
sp. THPS1 is a novel strain isolated from a high-temperature hot spring in Thailand, exhibiting distinctive genomic features that enable adaptation to an extreme environment. This study aimed to characterize the genomic and functional attributes of sp.
View Article and Find Full Text PDFMicroorganisms
November 2024
Department of Entomology, College of Agriculture, Life and Environmental Sciences, University of Arizona, Tucson, AZ 85719, USA.
Hard ticks (family Ixodidae) are one of the most predominant arthropod disease vectors worldwide, second only to mosquitoes. In addition to harboring animal and human pathogens, ticks are known to carry a microbial community constituted of non-pathogenic organisms, which includes maternally inherited intracellular endosymbionts and other environmentally acquired extracellular microorganisms. These microbial communities, which include bacteria, viruses, protozoans, and fungi-with often commensal, mutualistic, or parasitic associations with the tick-comprise the tick microbiome, bacteria being the most studied community.
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