Since its recent discovery, Bourbon virus has been isolated from a human and ticks. To assess exposure of potential vertebrate reservoirs, we assayed banked serum and plasma samples from wildlife and domestic animals in Missouri, USA, for Bourbon virus-neutralizing antibodies. We detected high seroprevalence in raccoons (50%) and white-tailed deer (86%).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711231PMC
http://dx.doi.org/10.3201/eid2509.181902DOI Listing

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Department of Botany and Microbiology, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.

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We report a patient in North Carolina, USA, with Heartland virus infection whose diagnosis was complicated by previous Ehrlichia chaffeensis infection. We identified E. ewingii-infected and Bourbon virus-infected tick pools at the patient's residence.

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Article Synopsis
  • - Bourbon virus is a virus transmitted by ticks that can lead to illness in humans.
  • - Cases have been documented in Kansas, Oklahoma, and Missouri, with antibody detection in patients from North Carolina.
  • - The prevalence of Bourbon virus infections may be underestimated, indicating a need for better diagnostic tools and monitoring systems.
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Bourbon virus (BRBV) is an emerging pathogen that can cause severe and fatal disease in humans. BRBV is vectored by (lone star ticks), which are widely distributed across the central, southern, and eastern United States. Wildlife species are potentially important for the maintenance and transmission of BRBV, but little is known about which species are involved, and what other factors play a role in the exposure to BRBV.

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Emerging tick-borne viruses such as Powassan virus (POWV), Bourbon virus (BRBV), and Heartland virus (HRTV), whilst rare, can cause severe health problems in humans. While limited clinical cases have been reported thus far in Virginia, the presence of tick-borne viruses poses a serious health threat, and the extent of their prevalence in Virginia is unknown. Here, we sought evidence of POWV, BRBV, and HRTV exposure in Virginia via a serological assessment of wildlife and livestock.

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