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Microfluidic and Computational Tools for Neurodegeneration Studies.
Annu Rev Chem Biomol Eng
January 2025
1Department of Chemical & Biomolecular Engineering, North Carolina State University, Raleigh, North Carolina, USA; email:
Understanding the molecular, cellular, and physiological components of neurodegenerative diseases (NDs) is paramount for developing accurate diagnostics and efficacious therapies. However, the complexity of ND pathology and the limitations associated with conventional analytical methods undermine research. Fortunately, microfluidic technology can facilitate discoveries through improved biomarker quantification, brain organoid culture, and small animal model manipulation.
View Article and Find Full Text PDFEvaluation and Comparison of the Academic Quality of Open-Access Mega Journals and Authoritative Journals: Disruptive Innovation Evaluation.
J Med Internet Res
January 2025
Henan Research Center for Science Journals, Xinxiang Medical University, Xinxiang, China.
Background: Some scholars who are skeptical about open-access mega journals (OAMJs) have argued that low-quality papers are often difficult to publish in more prestigious and authoritative journals, and OAMJs may be their main destination.
Objective: This study aims to evaluate the academic quality of OAMJs and highlight their important role in clinical medicine. To achieve this aim, authoritative journals and representative OAMJs in this field were selected as research objects.
The Association Between the Digital Divide and Health Inequalities Among Older Adults in China: Nationally Representative Cross-Sectional Survey.
J Med Internet Res
January 2025
School of Public Health, Capital Medical University, Beijing, China.
Background: Health inequalities among older adults become increasingly pronounced as aging progresses. In the digital era, some researchers argue that access to and use of digital technologies may contribute to or exacerbate these existing health inequalities. Conversely, other researchers believe that digital technologies can help mitigate these disparities.
View Article and Find Full Text PDFInavolisib Therapy in Advanced Breast Cancer.
N Engl J Med
January 2025
University of Illinois Chicago, Chicago, IL
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