Synthesis of Four Illudalane Sesquiterpenes Utilizing a One-Pot Diels-Alder/Oxidative Aromatization Sequence.

Org Lett

National Demonstration Center for Experimental Chemical Engineering Comprehensive Education, School of Chemical Engineering and Technology, North University of China, Taiyuan 030000, P.R. China.

Published: September 2019

The concise, divergent total syntheses of four illudalane sesquiterpenes using an indanone as the key intermediate are reported. The key elements in these total syntheses, which involve only four to six operational steps, consist of a Suzuki cross-coupling and a one-pot Diels-Alder/oxidative aromatization reaction.

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http://dx.doi.org/10.1021/acs.orglett.9b02511DOI Listing

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