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Differentiation of mesenchymal stem cells towards lens epithelial stem cells based on three-dimensional bio-printed matrix.
Front Cell Dev Biol
January 2025
Senior Department of Ophthalmology, The Third Medical Center of PLA General Hospital, PLA General Hospital and PLA Medical College, Beijing, China.
The high risks of traumatic cataract treatments promoted the development of the concept of autologous lens regeneration. Biochemical cues can influence the cellular behavior of stem cells, and in this case, biophysical cues may be the important factors in producing rapid activation of cellular behavior. Here we bio-printed mesenchymal stem cells (MSCs) using a commonly used bioink sodium alginate-gelatin blends, and investigated the induction effect of MSC differentiation towards lens epithelial stem cells (LESCs) under a combination of biochemical cues and biophysical cues.
View Article and Find Full Text PDFClinical efficacy of antibiotic-loaded bone cement and negative pressure wound therapy in multidrug-resistant organisms diabetic foot ulcers: a retrospective analysis.
Front Cell Infect Microbiol
January 2025
Department of Orthopedics, Fuyang City People's Hospital, Fuyang, China.
Objective: The purpose of this study was to investigate the clinical efficacy of antibiotic-loaded bone cement (ALBC) combined with Negative pressure wound therapy (NPWT) aspiration technique in the treatment of multidrug-resistant diabetic foot ulcers (MDRO-DFUs).
Methods: A retrospective analysis of the clinical data of 80 patients with MDROs-DFU who were used Vacuum sealing drainage (VSD) as NPWT excipient and met the inclusion criteria from January 2019 to January 2024 at our hospital. Patients were divided into an experimental group and a control group, with 40 cases in each.
The effects of sex and load on quantifying the bilateral force deficit during an upper body Wingate test.
Front Sports Act Living
January 2025
School of Human Kinetics and Recreation, Memorial University of Newfoundland, St. John's, NL, Canada.
Introduction: The bilateral deficit (BLD) is a reduction in the amount of force during a bilateral task vs. the total force from the unilateral limbs performing the same task. We quantified the BLD during an upper body Wingate Anaerobic Test (WAnT) and evaluated the influence of sex and load on the BLD in force.
View Article and Find Full Text PDFBasic investigation on fluorescence properties of soybeans in response to different external defects.
Spectrochim Acta A Mol Biomol Spectrosc
January 2025
Graduate School of Science and Technology, Niigata University, 8050 Ikarashi 2-no-cho, Nishi-ku, Niigata City, Niigata 950-2181, Japan. Electronic address:
To investigate the fluorescent properties of defects found on the surface of harvested soybeans, the front-face method was used to measure the Excitation Emission Matrix (EEM) on 106 samples of two varieties of soybeans to evaluate fluorescent properties according to defect type. The EEM showed four main peaks at Excitation/Emission (Ex/Em): 350-430 nm/420-510 nm, 410-450 nm/460-530 nm, 260-290 nm/300-350 nm and 210-230 nm/310-340 nm. In the Diseased, Pest, and Denatured (Black) soybeans, the above four main peaks were weakened.
View Article and Find Full Text PDFLarge-scale production of infective larvae from engorged .
Front Trop Dis
December 2024
Parasite and Vector Research Unit (PAVRU), Department of Microbiology and Parasitology, University of Buea, Buea, Cameroon.
Background: is transmitted by species and affects hundred millions of inhabitants in about 33 countries in sub-Saharan Africa. It is known that Mansonellosis due to do not result in a clear clinical picture, but down-regulates the immunity of patients predisposing them to other diseases like tuberculosis, HIV and malaria or damping vaccine efficacy. However, research about novel drugs against this filarial nematode is missing because of the lack of parasite material.
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