Iodonium(III) salts bearing uracil moieties have recently appeared in the literature, but their structural scope and utilization are limited because of their hygroscopic characteristics. In this study, we describe our detailed investigations for synthesizing a series of uracil iodonium(III) salts derived with various structural motifs and counterions. These new compounds have been utilized as attractive synthetic modules in constructing functionalized nucleobase and nucleosides
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6749211 | PMC |
| http://dx.doi.org/10.3390/molecules24173034 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A single-plasmid-based, easily curable CRISPR/Cas9 system for rapid, iterative genome editing in Pseudomonas putida KT2440.
Microb Cell Fact
December 2024
Department of Chemical Engineering, University of Waterloo, Waterloo, Canada.
Background: Pseudomonas putida KT2440, a non-pathogenic soil bacterium, is a key platform strain in synthetic biology and industrial applications due to its robustness and metabolic versatility. Various systems have been developed for genome editing in P. putida, including transposon modules, integrative plasmids, recombineering systems, and CRISPR/Cas systems.
View Article and Find Full Text PDFOligoDistiller: A Platform Agnostic Software Tool for MS and MS Data Analysis of Complex Oligonucleotides and Their Impurities.
Anal Chem
December 2024
Janssen Pharmaceutica N.V., Turnhoutseweg 30, 2340 Beerse, Belgium.
Oligonucleotides are currently one of the most rapidly advancing classes of therapeutic modalities. Understanding critical quality attributes, such as the impurity profile, stability, potential metabolites, and sequence conformity, is the key to their ultimate success. To obtain the information presented above, liquid chromatography-mass spectrometry (LC-MS) is often employed.
View Article and Find Full Text PDFGenerative adversarial networks with texture recovery and physical constraints for remote sensing image dehazing.
Sci Rep
December 2024
College of Electrical Engineering, Northeast Electric Power University, Jilin, 132012, China.
The scattering of tiny particles in the atmosphere causes a haze effect on remote sensing images captured by satellites and similar devices, significantly disrupting subsequent image recognition and classification. A generative adversarial network named TRPC-GAN with texture recovery and physical constraints is proposed to mitigate this impact. This network not only effectively removes haze but also better preserves the texture information of the original remote sensing image, thereby enhancing the visual quality of the dehazed image.
View Article and Find Full Text PDFMetabolic Engineering of Corynebacterium glutamicum for High-Level Production of 1,5-Pentanediol, a C5 Diol Platform Chemical.
Adv Sci (Weinh)
December 2024
Department of Chemical Engineering and Materials Science, Graduate Program in System Health Science and Engineering, Ewha Womans University, Seoul, 03760, Republic of Korea.
The biobased production of chemicals is essential for advancing a sustainable chemical industry. 1,5-Pentanediol (1,5-PDO), a five-carbon diol with considerable industrial relevance, has shown limited microbial production efficiency until now. This study presents the development and optimization of a microbial system to produce 1,5-PDO from glucose in Corynebacterium glutamicum via the l-lysine-derived pathway.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!