The use of dietary supplements (DSs) is increasing in the U.S. As such, it is crucial for consumers, clinicians, and researchers to be able to find information about DS products. However, labeling regulations allow great variability in DS product names, which makes searching for this information difficult. Following the RxNorm drug name normalization model, we developed a rule-based natural language processing system to normalize DS product names using pattern templates. We evaluated the system on product names extracted from the Dietary Supplement Label Database. Our system generated 136 unique templates and obtained a coverage of 72%, a 32% increase over the existing RxNorm model. Manual review showed that our system achieved a normalization accuracy of 0.86. We found that the normalization of DS product names is feasible, but more work is required to improve the generalizability of the system.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6792000 | PMC |
http://dx.doi.org/10.3233/SHTI190253 | DOI Listing |
Anal Bioanal Chem
January 2025
ICF International Contractor in support of the Office of Dietary Supplements, National Institutes of Health, Bethesda, MD, USA.
Rigorous research on the health effects of dietary supplements and related nutritional interventions requires thorough chemical characterization of complex matrices for their composition of macro- and micronutrients, botanical phytochemicals, and potential contaminants. Reference materials (RMs) with metrologically traceable values for these specific properties are ideal analytical tools to ensure requisite chemical measurements are reliable. However, identifying and comparing appropriate RMs for studying dietary ingredients and their metabolites is challenging, creating a barrier to reproducible regulatory testing and research.
View Article and Find Full Text PDFiScience
January 2025
Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
We and others previously found that a misannotated long noncoding RNA encodes for a conserved mitochondrial transmembrane microprotein named Mitoregulin (Mtln). Beyond an established role for Mtln in lipid metabolism, Mtln has been shown to broadly influence mitochondria, boosting respiratory efficiency and Ca retention capacity, while lowering ROS, yet the underlying mechanisms remain unresolved. Prior studies have identified possible Mtln protein interaction partners; however, a lack of consensus persists, and no claims have been made about Mtln's structure.
View Article and Find Full Text PDFCurr Dev Nutr
January 2025
United States Army Research Institute of Environmental Medicine (USARIEM), Military Performance Division, Natick, MA, United States.
Background: Dietary intake is a modifiable factor linked to short-term and long-term health. The Healthy Eating Index (HEI) is an objective measure to assess diet quality and population-level comparisons, like military to civilian.
Objectives: This study aimed to characterize diet quality of early-career and mid-career female soldiers compared with that of age-matches and sex-matched civilians and to link indicators of cardiometabolic disease risk to dietary outcomes and health status.
Acad Radiol
January 2025
Molecular Imaging Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD (O.T.E., E.C.Y., B.D.S., S.A.H., D.G.G., Y.L., M.J.B., P.L.C., B.T.). Electronic address:
Rationale And Objectives: Accurate preoperative mpMRI-based detection of extraprostatic extension (EPE) in prostate cancer (PCa) is critical for surgical planning and patient outcomes. This study aims to evaluate the impact of endorectal coil (ERC) use on the diagnostic performance of mpMRI in detecting EPE.
Materials And Methods: This retrospective study with prospectively collected data included participants who underwent mpMRI and subsequent radical prostatectomy for PCa between 2007 and 2024.
iScience
January 2025
Vivian L. Smith Department of Neurosurgery, McGovern Medical School at UT Health Houston, Houston, TX 77030, United States of America.
Speech production engages a distributed network of cortical and subcortical brain regions. The supplementary motor area (SMA) has long been thought to be a key hub in coordinating across these regions to initiate voluntary movements, including speech. We analyzed direct intracranial recordings from 115 patients with epilepsy as they articulated a single word in a subset of trials from a picture-naming task.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!