As the problem of drug abuse intensifies in the U.S., many studies that primarily utilize social media data, such as postings on Twitter, to study drug abuse-related activities use machine learning as a powerful tool for text classification and filtering. However, given the wide range of topics of Twitter users, tweets related to drug abuse are rare in most of the datasets. This imbalanced data remains a major issue in building effective tweet classifiers, and is especially obvious for studies that include abuse-related slang terms. In this study, we approach this problem by designing an ensemble deep learning model that leverages both word-level and character-level features to classify abuse-related tweets. Experiments are reported on a Twitter dataset, where we can configure the percentages of the two classes (abuse vs. non abuse) to simulate the data imbalance with different amplitudes. Results show that our ensemble deep learning models exhibit better performance than ensembles of traditional machine learning models, especially on heavily imbalanced datasets.
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http://dx.doi.org/10.3233/SHTI190204 | DOI Listing |
Biomedicines
January 2025
Perception, Robotics, and Intelligent Machines Lab (PRIME), Department of Computer Science, Université de Moncton, Moncton, NB E1A 3E9, Canada.
Retinal blood vessel segmentation plays an important role in diagnosing retinal diseases such as diabetic retinopathy, glaucoma, and hypertensive retinopathy. Accurate segmentation of blood vessels in retinal images presents a challenging task due to noise, low contrast, and the complex morphology of blood vessel structures. In this study, we propose a novel ensemble learning framework combining four deep learning architectures: U-Net, ResNet50, U-Net with a ResNet50 backbone, and U-Net with a transformer block.
View Article and Find Full Text PDFJ Imaging
January 2025
Department of Obstetrics and Gynecology, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand.
The current process of embryo selection in in vitro fertilization is based on morphological criteria; embryos are manually evaluated by embryologists under subjective assessment. In this study, a deep learning-based pipeline was developed to classify the viability of embryos using combined inputs, including microscopic images of embryos and additional features, such as patient age and developed pseudo-features, including a continuous interpretation of Istanbul grading scores by predicting the embryo stage, inner cell mass, and trophectoderm. For viability prediction, convolution-based transferred learning models were employed, multiple pretrained models were compared, and image preprocessing techniques and hyperparameter optimization via Optuna were utilized.
View Article and Find Full Text PDFCurr Issues Mol Biol
January 2025
College of Pharmacy, Chongqing Medical University, Chongqing 400016, China.
P21-activated kinase 4 (PAK4) plays a crucial role in the proliferation and metastasis of various cancers. However, developing selective PAK4 inhibitors remains challenging due to the high homology within the PAK family. Therefore, developing highly selective PAK4 inhibitors is critical to overcoming the limitations of existing inhibitors.
View Article and Find Full Text PDFMed Biol Eng Comput
January 2025
Artificial Intelligence Lab, School of Computer and Information Sciences, University of Hyderabad, Hyderabad, 500046, India.
The generalization of deep learning (DL) models is critical for accurate lesion segmentation in breast ultrasound (BUS) images. Traditional DL models often struggle to generalize well due to the high frequency and scale variations inherent in BUS images. Moreover, conventional loss functions used in these models frequently result in imbalanced optimization, either prioritizing region overlap or boundary accuracy, which leads to suboptimal segmentation performance.
View Article and Find Full Text PDFBMC Cancer
January 2025
Institute of Medical Information, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Background: Identifying high risk factors and predicting lung cancer incidence risk are essential to prevention and intervention of lung cancer for the elderly. We aim to develop lung cancer incidence risk prediction model in the elderly to facilitate early intervention and prevention of lung cancer.
Methods: We stratified the population into six subgroups according to age and gender.
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