Objective: Consumption of date fruits leads to chemical changes in saliva, including variations in pH values. We conducted this study to assess the effect of the consumption of different types of dates on salivary pH.
Methods: We recruited 15 children (aged 6-15 years) who were instructed to consume one piece of specific types of dates (Safree, Nabtat Seif, Khalas, Sukkari, and Segae) for 5 consecutive days. On the 6th and 7th days, the children consumed a quarter of a grapefruit (positive control) and chewed on a sterilised cotton pellet (negative control), respectively. Salivary samples from unstimulated kids were collected at least 1 h after breakfast every day and the salivary pH was recorded.
Results: When compared with the pH values before date consumption, the lowest mean salivary pH value among the date-consuming groups 5 min after salivary stimulation was noted after the consumption of Khalas (6.26), followed by those after consumption of Safree (6.31), Nabtat Seif (6.36), Segae (6.44), and Sukkari (6.45). The highest difference in mean values was observed for Khalas (.47), followed by those for Sukkari (.45), Nabtat Saif (.44), Segae (.38), and Safree (.35). The pH of saliva collected after grapefruit consumption was the lowest, whereas chewing cotton pellets led to an increased salivary pH.
Conclusion: This study showed a decrease in the salivary pH following date consumption, but not to a value as low as the critical value. These findings suggest that dates do not have detrimental effects on salivary parameters.
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http://dx.doi.org/10.1016/j.jtumed.2019.04.005 | DOI Listing |
Int J Surg
January 2025
The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China.
Colorectal cancer (CRC) is a malignant tumor that originates from the epithelial cells of the colon and rectum. Global epidemiological data shows that in 2020, the incidence and mortality rate of CRC ranked third and second, respectively, posing a serious threat to people's health and lives. The factors influencing CRC are numerous and can be broadly categorized as modifiable and non-modifiable based on whether they can be managed or intervened upon.
View Article and Find Full Text PDFInt J Surg
January 2025
Department of Pancreatic Surgery, Fudan University Shanghai Cancer Center, Shanghai, China.
Background: Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal diseases. Although several chemotherapy regimens have been developed over the past decades, few targeted therapies have shown a significant improvement in overall survival, partly due to the identification of PDAC as a single disease.
Methods: Combining metabolomic analysis and immunohistochemistry staining with Oil Red O staining, analysis for the oxygen consumption rate and extracellular acidification rate, we stratified pancreatic cancer cells into two subtypes.
JAMA Pediatr
January 2025
Vascular Assessment and Management Service, Department of Anaesthesia and Pain, Queensland Children's Hospital, Children's Health Queensland Hospital and Health Service, Queensland, Australia.
Importance: Pediatric peripheral intravenous catheter (PIVC) insertion can be difficult and time-consuming, frequently requiring multiple insertion attempts and often resulting in increased anxiety, distress, and treatment avoidance among children and their families. Ultrasound-guided PIVC insertion is a superior alternative to standard technique (palpation and visualization) in high-risk patients.
Objective: To compare first-time insertion success of PIVCs inserted with ultrasound guidance compared with standard technique (palpation and visualization) across all risk categories in the general pediatric hospital population.
JAMA Netw Open
January 2025
Amazon Health Services, Seattle, Washington.
Importance: Medication nonadherence imposes high morbidity, mortality, and costs but is challenging to address given its multiple causes. Subscription models are increasingly used in health care to encourage healthy behaviors; in January 2023, Amazon Pharmacy launched RxPass, a subscription program offering Amazon Prime members (hereafter, company members) in 45 states access to 60 common generic medications for a flat $5 monthly fee.
Objective: To evaluate the associations of program enrollment with medication refills, days' supply, and out-of-pocket costs.
Matern Child Health J
January 2025
Department of Epidemiology and Biostatistics, Michigan State University, Fee Hall West Wing; 909 Wilson Rd, East Lansing, MI, 48824, USA.
Background: Dental care before pregnancy is critical for preventing poor oral health, which is associated with adverse pregnancy outcomes. People with low incomes, however, may face insurance-related barriers to obtaining dental care. Medicaid expansion under the Affordable Care Act increased access to dental care utilization among adults with low incomes.
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