This institutional case control study was carried out to compare choroidal vascularity (CV) in amblyopic eyes, fellow eyes, and control eyes in children with unilateral hyperopic amblyopia. Sixty-four eyes of 32 childeren with unilateral anisometropic hyperopic amblyopia and 38 eyes of 19 healthy children (controls), aged 3 to 16 years. Subfoveal choroidal thickness (CT) and CV were measured using spectral domain optical coherence tomography. The mean subfoveal CT of amblyopic eyes (338.9 ± 60.0 μm) was greater than that of fellow eyes (315.3 ± 63.3 μm, P = 0.043) and control eyes (313.0 ± 42.1 μm, P = 0.025). The mean CV of amblyopic eyes (0.715 ± 0.020) was greater than that of control eyes (0.700 ± 0.020, P < 0.001). While a positive correlation between CT and CV was found in normal eyes (r = 0.470, P = 0.004), a strong negative correlation existed in amblyopic eyes (r = -0.684, P < 0.001). In conclusion, although mean CV was higher in amblyopic eyes, the negative correlation between CT and CV may suggests insufficient blood supply to the outer retina and choroid in the affected eyes of patients with unilateral anisometropic hyperopic amblyopia.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704087 | PMC |
| http://dx.doi.org/10.1038/s41598-019-48613-3 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Real-World Evidence on Digital Therapeutics in Pediatric Amblyopia: Insights into Rapid Axial Elongation Risk.
Ophthalmology
January 2025
State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, 510060, China. Electronic address:
Objective: To evaluate the impact of daily digital therapeutics (DTx) on the risk of rapid axial elongation (RAE) in children with amblyopia using real-world data.
Design: Retrospective cohort study.
Subjects: A total of 1,394 children aged 3 to 12 years with amblyopia, of which 477 received DTx.
Ocular findings in Baraitser-Winter syndrome with a de novo mutation in the ACTG1 gene: a case report.
BMC Ophthalmol
December 2024
Department of Ophthalmology, Daegu catholic university school of medicine, Daegu, Korea.
Background: Baraitser-Winter syndrome (BWS) is rare, and no previous reports have described the visual course of patients with this condition. Herein, we report the long-term visual outcomes and ocular features of a 6-year-old patient diagnosed with BWS.
Case Presentation: A 6-year-old female patient visited our clinic complaining of low vision.
Brazilian best practice guidelines for amblyopia diagnosis and management.
Arq Bras Oftalmol
November 2024
Pediatric Ophthalmology Sector, Hospital de Olhos do Paraná, Curitiba, PR, Brazil.
This study aimed to propose a guideline for amblyopia treatment and follow-up. Studies show that amblyopia leads to a series of perceptual deficits, including loss of visual acuity, stereoacuity, and contrast sensitivity. Perceptual changes are also found in the sound eye, such as those involving the types of motion perception.
View Article and Find Full Text PDFOcular manifestations of craniosynostosis in Saudi Arabia.
J Fr Ophtalmol
November 2024
Division of Plastic Surgery, Department of Surgery, King Saud University Medical City, King Saud University, Riyadh, Saudi Arabia.
Article Synopsis
- The study investigates the ophthalmic abnormalities in Arab children diagnosed with craniosynostosis, noting a lack of previous research in Middle Eastern populations.
- It involved 31 children, revealing that a significant proportion experienced refractive errors and papilledema, which improved following craniofacial surgery.
- The findings emphasize the importance of regular eye evaluations and timely referrals to address visual function issues associated with craniosynostosis in this demographic.
Characteristics of astigmatism in school-age children aged 5 to 13 years in northeast Sichuan: a cross-sectional school-based study.
Transl Pediatr
July 2024
Department of Optometry, North Sichuan Medical College, Nanchong, China.
Background: Astigmatism is closely associated with myopia progression, vision loss, eye fatigue and amblyopia, which seriously endangers children's eye health. This study aims to investigate the prevalence and characteristic distribution of astigmatism in children in Langzhong City, providing valuable insights for allocating resources and develop prevention and control strategies.
Methods: A cross-sectional study and random sampling survey were conducted.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!