Objective: commonly occurs in the stomach, but localizations outside the stomach and related diseases have also been investigated. However, the relationship between and gallstones remains controversial. We aimed to investigate the relationships between in the stomach and the gallbladder and gallstones.

Methods: This prospective case-control study included patients who underwent cholecystectomy because of gallstones, pancreatic head cancer, or hepatic resection. The patients were separated into two groups according to the detection of in gallbladder samples using Giemsa staining. Stomach status was based on previous gastroscopy.

Results: The study enrolled 60 patients, comprising 27 patients with gallstones and 33 without. There was no significant difference in the incidence of gallstones between patients with or without in the stomach or gallbladder. Furthermore, the presence of in the stomach was measured in 14 patients and was significantly correlated with in the gallbladder.

Conclusion: The current study showed no relationship between the occurrence of gallstones and the presence of in either the gallbladder or the stomach. In contrast to previous reports, this suggests that does not play a role in the development of gallstones.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6833382PMC
http://dx.doi.org/10.1177/0300060519847345DOI Listing

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