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EUS-Directed transDuodenal ERCP in Concomitant Gastric Outlet and Biliary Obstruction.

Gastrointest Endosc

December 2024

Virginia Tech Carilion, Division of Gastroenterology, Roanoke, Virginia.

Background And Aims: Patients with concomitant gastric outlet obstruction (GOO) and biliary obstruction often have limited management options, particularly in the setting of severe debility. We detail the use of EUS guided gastro-duodenal placement of lumen apposing metal stent (LAMS) as a conduit for transduodenal ERCP: EUS-Directed transDuodenal ERCP (EDDE).

Methods: Nine patients that developed GOO with indwelling biliary metal stents or with anticipated biliary stent placement were retrospectively included.

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Imaging followed by endoscopic ultrasound (EUS)-guided therapy has become the preferred modality for treating pancreatic pseudocysts over surgical or radiological interventions. However, there continues to be a lack of consensus regarding the utility of endoscopic retrograde cholangiopancreatography (ERCP) before and after cyst drainage. We describe 4 cases of large pancreatic pseudocyst causing extrinsic biliary obstruction treated successfully with endoscopic cystogastrostomy decompression using a lumen-apposing self-expandable metal stent (LAMS) without ERCP.

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Endoscopic ultrasound-guided biliary drainage percutaneous transhepatic biliary drainage for malignant biliary obstruction after endoscopic retrograde cholangiopancreatography failure.

World J Gastrointest Surg

November 2024

Department of Interventional Therapy, National Cancer Center, National Clinical Research Center for Cancer, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.

In a recent issue of the , a meta-analysis investigated the safety and efficacy of electrocautery-enhanced lumen-apposing metal stent (ECE-LAMS) implantation for managing malignant biliary obstruction following failed endoscopic retrograde cholangiopancreatography. This manuscript endeavors to offer a comprehensive look at the progression of endoscopic ultrasound-guided biliary drainage (EUS-BD) technologies, weighing their merits and drawbacks against traditional percutaneous methods. Several meta-analyses and randomized controlled trials have compared the performance of EUS-BD and percutaneous transhepatic cholangiodrainage (PTCD).

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Article Synopsis
  • Cholecystectomy is the standard treatment for average-risk patients with acute cholecystitis, but high-risk patients may benefit from alternatives like PT-GBD and EUS-GBD.
  • PT-GBD has limitations and is not suitable for every patient, especially those too ill to be transferred, making bedside EUS-GBD a viable option.
  • A case series showed that bedside EUS-GBD in the ICU was safe and effective for critically ill patients, but all required comfort care due to their serious conditions, suggesting the need for more research in this area.
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