The recent surge of interest in brain-inspired computing and power-efficient electronics has dramatically bolstered development of computation and communication using neuron-like spiking signals. Devices that can produce rapid and energy-efficient spiking could significantly advance these applications. Here we demonstrate direct current or voltage-driven periodic spiking with sub-20 ns pulse widths from a single device composed of a thin VO film with a metallic carbon nanotube as a nanoscale heater, without using an external capacitor. Compared with VO-only devices, adding the nanotube heater dramatically decreases the transient duration and pulse energy, and increases the spiking frequency, by up to 3 orders of magnitude. This is caused by heating and cooling of the VO across its insulator-metal transition being localized to a nanoscale conduction channel in an otherwise bulk medium. This result provides an important component of energy-efficient neuromorphic computing systems and a lithography-free technique for energy-scaling of electronic devices that operate via bulk mechanisms.
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http://dx.doi.org/10.1021/acs.nanolett.9b01554 | DOI Listing |
Neural Comput
January 2025
Electronics and Computer Science, University of Southampton, Southampton SO17 1BJ, U.K.
The creation of future low-power neuromorphic solutions requires specialist spiking neural network (SNN) algorithms that are optimized for neuromorphic settings. One such algorithmic challenge is the ability to recall learned patterns from their noisy variants. Solutions to this problem may be required to memorize vast numbers of patterns based on limited training data and subsequently recall the patterns in the presence of noise.
View Article and Find Full Text PDFFront Nutr
December 2024
Department of Microbiology, SRM Medical College Hospital and Research Centre, SRM IST, Kattankulathur, Tamil Nadu, India.
Background: Gestational diabetes mellitus (GDM) poses significant risks to both maternal and fetal health, including a heightened risk of developing type 2 diabetes (T2DM) in the future. Effective management often involves dietary changes, such as food-order, where vegetables are consumed first, followed by proteins, and then carbohydrates last. This study investigates whether food sequence improves glycemic control in women with GDM by slowing carbohydrate absorption, reducing glucose spikes, and enhancing insulin sensitivity.
View Article and Find Full Text PDFNeurophysiol Clin
January 2025
Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, PR China. Electronic address:
Objectives: In the present study with a large cohort, we aimed to characterize intracerebral seizure onset patterns (SOP) of mesial temporal lobe epilepsy (mTLE), with or without hippocampal sclerosis (HS) as identified via magnetic resonance imaging (MRI).
Methods: We retrospectively analyzed 255 seizures of 76 consecutive patients with mTLE explored by stereoelectroencephalography (SEEG), including HS-mTLE (n = 52) and non-HS- mTLE (n = 24). Relevant results were obtained by a combination of spectral analysis and manual review.
Front Neurosci
December 2024
School of Integrated Circuits, Peking University, Beijing, China.
Spiking Neural Networks (SNNs) are typically regards as the third generation of neural networks due to their inherent event-driven computing capabilities and remarkable energy efficiency. However, training an SNN that possesses fast inference speed and comparable accuracy to modern artificial neural networks (ANNs) remains a considerable challenge. In this article, a sophisticated SNN modeling algorithm incorporating a novel dynamic threshold adaptation mechanism is proposed.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
January 2025
Department of Neuroscience, Farber Institute for Neuroscience and Jefferson Synaptic Biology Center, Sidney Kimmel Medical College of Thomas Jefferson University, Philadelphia, PA 19107.
Use-dependent spike broadening (UDSB) results from inactivation of the voltage-gated K (Kv) channels that regulate the repolarization of the action potential. However, the specific signaling and molecular processes that modulate UDSB have remained elusive. Here, we applied an adeno-associated viral vector approach and dynamic clamping to conclusively demonstrate how multisite phosphorylation of the N-terminal inactivation domain (NTID) of the Kv3.
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