Bioceramic cement in the filling of bone defects in rats.

Acta Cir Bras

PhD, Professional Masters in Sciences Applied to Health, UNIVÁS, Pouso Alegre-MG, Brazil. Scientific and intellectual content of the study, analysis and interpretation of data, manuscript writing, critical revision, final approval.

Published: August 2019

Purpose: To evaluate PBS®MCIMMO cement in the filling of bone defects.

Methods: Thirty-six adult male Wistar rats were divided into three groups of twelve individuals each (group 1, group 2 and group 3). In all groups, a bone failure in the femur was induced, 2.0 mm wide and 7.0 mm deep. In group 1, the PBS®MCIMMO cement was applied to the bone defect produced and a titanium implant (CONNECTION®) 1.5 mm thick and 6 mm long was installed. In group 2, only the PBS® CIMMO cement was installed. In group 3, only bone failure was performed. Kruskal Wallis tests were performed to compare the mean area among the three groups.

Results: In all comparisons, significance was observed for group 2 (p = 0.0014-0.0026).

Conclusion: The PBS®CIMMO cement induced bone neoformation, and integration between the newly formed bone, cement, and implant was observed.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6705333PMC
http://dx.doi.org/10.1590/s0102-865020190060000001DOI Listing

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