Objective: To standardize the investigation and clinical management of women with laboratory and/or clinical abnormalities suggestive of thrombophilia, in order to optimize antithrombotic approach and indication of laboratory tests.
Methodology: A discussion was carried out among 107 physicians (gynecologists/obstetricians, hematologists and vascular surgeons) present at a forum held at the Hospital Israelita Albert Einstein, in São Paulo (SP), Brazil. As a minimum criterion, 80% agreement was established in the voting to each recommendation of conduct in the final document. The cases in which there was agreement below 80% were discussed again, reaching a consensual agreement of conduct for the document writing.
Conclusion: The standardization of an institutional consensus of suggestions of clinical approach contributes to a better management of the group to be evaluated and minimizes risks of intercurrent events. This was the first national consensus on the investigation of thrombophilia in women.
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http://dx.doi.org/10.31744/einstein_journal/2019AE4510 | DOI Listing |
Ann Hematol
January 2025
Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School (MHH), Hannover, Germany.
The prefibrotic phase of primary myelofibrosis (pre-PMF) represents a distinct subentity within the spectrum of myeloproliferative neoplasms (MPNs), recognized by the World Health Organization (WHO) and the International Consensus Classification (ICC). Pre-PMF is characterized by unique morphological, clinical, and molecular features, distinguishing it from essential thrombocythemia (ET) and overt myelofibrosis (overt-PMF). The diagnostic process for pre-PMF relies on bone marrow histology, identification of molecular mutations and exclusion of other myeloid neoplasms.
View Article and Find Full Text PDFInt J Ment Health Nurs
February 2025
University of Technology Sydney, Sydney, New South Wales, Australia.
The clinical reasoning cycle was designed to guide nursing care and assist with clinical-reasoning and decision-making. While originally developed with an acute health lens, more recently an adapted version has been created for forensic mental health nurses. It is possible that such a framework may also be helpful for mental health nurses working in generalist settings.
View Article and Find Full Text PDFInt J Gynaecol Obstet
January 2025
Guy's & St Thomas' Hospital Foundation Trust, London, UK.
The number of retractions of randomized clinical trials (RCTs) following post-publication allegations of misconduct is increasing. To address this issue, we aimed to establish an international multistakeholder consensus on post-publication integrity concerns related to RCTs. After prospective registration (https://osf.
View Article and Find Full Text PDFJ Clin Res Pediatr Endocrinol
January 2025
Turkish Pediatric Endocrinology and Diabetes Society, Thyroid Research Group, Türkiye.
Objective: This study was conducted to assess the perspectives of pediatric endocrinologists in Türkiye on the management of congenital hypothyroidism (CH) and to analyze the potential impact of work environment and professional experience on different attitudes.
Methods: The members of the Turkish Society for Pediatric Endocrinology and Diabetes were invited to participate in an online survey. An evaluation was made by obtaining survey responses from 95 (19%) of 502 members.
J Interpers Violence
January 2025
University of Vigo, Ourense, Spain.
The recent reconceptualization of the phenomenon of sexting between consensual and nonconsensual represents a relevant turning point in identifying and addressing nonconsensual sexting behaviors as online sexual violence. These practices of nonconsensual sexting, therefore, represent forms of technology-facilitated sexual violence, incorporating the terms image-based sexual harassment (IBSH) and image-based sexual abuse (IBSA) to describe the distribution of self-produced sexualized images in the online sphere by adolescents, who use the online environment as their main socialization space. The objective of this investigation is dual.
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