Point-of-care (POC) detection and diagnostic platforms provide critical information about health and safety conditions in austere and resource-limited settings in which medical, military, and disaster relief operations are conducted. In this work, low-cost paper materials commonly used in POC devices are coated with liquid-infused polymer surfaces and folded to produce geometries that precisely localize complex liquid samples undergoing concentration by evaporation. Liquid-infused polymer surfaces were fabricated by infusing silicone-coated paper with a chemically compatible polydimethylsiloxane oil to create a liquid overlayer. Tests on these surfaces showed no remaining bacterial cells after exposure to a sliding droplet containing a concentrated solution of Escherichia coli or Staphylococcus aureus, while samples without a liquid layer showed adhesion of both microdroplets and individual bacterial cells. Folding of the paper substrates with liquid-infused polymer surfaces into several functional 3D geometries enabled a clean separation and simultaneous concentration of a liquid containing rhodamine dye into discrete, predefined locations. When used with bacteria, which are known for their ability to adhere to nearly any surface type, functional geometries with liquid-infused polymer surfaces concentrated the cells at levels significantly higher than geometries with dry control surfaces. These results show the potential of synergistically combining paper-based materials with liquid-infused polymer surfaces for the manipulation and handling of complex samples, which may help the future engineering of POC devices.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1116/1.5114804 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Comparative Study of Electrospun Polydimethylsiloxane Fibers as a Substitute for Fluorine-Based Polymeric Coatings for Hydrophobic and Icephobic Applications.
Polymers (Basel)
November 2024
Engineering Department, Campus de Arrosadía S/N, Public University of Navarre, 31006 Pamplona, Spain.
The development of superhydrophobic, waterproof, and breathable membranes, as well as icephobic surfaces, has attracted growing interest. Fluorinated polymers like PTFE or PVDF are highly effective, and previous research by the authors has shown that combining these polymers with electrospinning-induced roughness enhances their hydro- and ice-phobicity. The infusion of these electrospun mats with lubricant oil further improves their icephobic properties, achieving a slippery liquid-infused porous surface (SLIPS).
View Article and Find Full Text PDFAntifouling slippery liquid infused porous surface for surfactant-free PCR on digital microfluidics platform.
Talanta
January 2025
DTU Bioengineering, Technical University of Denmark, Kongens Lyngby, Denmark. Electronic address:
Article Synopsis
- Digital microfluidics technology can improve biological experiments but faces issues like biofouling that slow processes and cause contamination.
- Traditional solutions like surfactants reduce fouling but can disrupt biological reactions, reducing efficiency.
- This study shows that slippery liquid-infused porous surfaces (SLIPS) effectively prevent biofouling and enhance PCR performance in DMF devices, leading to faster experiments and reduced reagent usage without compromising reaction integrity.
Amyloid Proteins Adhesive for Slippery Liquid-Infused Porous Surfaces.
Macromol Rapid Commun
January 2025
Key Laboratory of Applied Surface and Colloid Chemistry, Ministry of Education, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an, 710119, China.
Biomimetic slippery liquid-infused porous surfaces (SLIPS) have emerged as a promising solution to solve the limitations of superhydrophobic surfaces, such as inadequate durability in corrosion protection and a propensity for frosting. However, the challenge of ensuring strong, lasting adhesion on diverse materials to enhance the durability of the lubricant layer remains. The research addresses this by leveraging amyloid phase-transitioned lysozyme (PTL) as an adhesive interlayer, conferring stable attachment of SLIPS across a variety of substrates, including metals, inorganics, and polymers.
View Article and Find Full Text PDFUltraslippery Surface for Efficient Fog Harvesting and Anti-Icing/Fouling.
Small
December 2024
Ministry of Education Key Laboratory for the Green Preparation and Application of Functional Materials, Hubei Key Laboratory of Polymer Materials, Hubei University, Wuhan, 430062, China.
The conventional Slippery Liquid Infused Porous Surface (SLIPS) encounters challenges such as silicone oil leakage and complex manufacturing of rough substrate structures. Thus, it is crucial to develop a lubricant that is highly adaptable and less prone to loss for surface structures; a temperature-controlled method of infusing oleogel into a superhydrophobic surface (SHS) is presented in this paper. This approach draws inspiration from the characteristics of Nepenthes pitcher plant structures, albeit without the need for intricate pore-making or nanowire structures.
View Article and Find Full Text PDFEstimation of the Structure of Hydrophobic Surfaces Using the Cassie-Baxter Equation.
Materials (Basel)
August 2024
Department of Structural Mechanics, Faculty of Civil Engineering, Environmental and Geodetic Sciences, Koszalin University of Technology, Sniadeckich Street 2, 75-453 Koszalin, Poland.
The effect of extreme water repellency, called the lotus effect, is caused by the formation of a Cassie-Baxter state in which only a small portion of the wetting liquid droplet is in contact with the surface. The rest of the bottom of the droplet is in contact with air pockets. Instrumental methods are often used to determine the textural features that cause this effect-scanning electron and atomic force microscopies, profilometry, etc.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!