Endangered species face a huge array of challenges, including the negative consequences of individuals having to breed with close genetic relatives. But just how costly is inbreeding in small populations? New research from an endangered bird species suggests that considering inbreeding could be crucial for conservation programmes.
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Predicting the impact of targeted fence removal on connectivity in a migratory ecosystem.
Ecol Appl
January 2025
Smithsonian National Zoo and Conservation Biology Institute, Conservation Ecology Center, Front Royal, Virginia, USA.
Fencing is one of the most widely utilized tools for reducing human-wildlife conflict in agricultural landscapes. However, the increasing global footprint of fencing exceeds millions of kilometers and has unintended consequences for wildlife, including habitat fragmentation, movement restriction, entanglement, and mortality. Here, we present a novel and quantitative approach to prioritize fence removal within historic migratory pathways of white-bearded wildebeest (Connochaetes taurinus) across Kenya's Greater Masai Mara Ecosystem.
View Article and Find Full Text PDFNovel Fast-Setting and Mechanically-Strong Calcium Phosphate Pulp-Capping Cement with Metformin Release to Enhance Dental Pulp Stem Cells.
Bioengineering (Basel)
December 2024
Department of Biomaterials and Regenerative Dental Medicine, University Maryland School of Dentistry, Baltimore, MD 21201, USA.
Traditional pulp-capping materials like mineral trioxide aggregate (MTA) offer excellent biocompatibility and sealing, but limitations such as prolonged setting time, low bioactivity, and high costs persist. Metformin, with its potential in craniofacial regeneration, could enhance dentin synthesis by targeting pulp cells. This study aimed to: (1) develop a calcium phosphate cement with chitosan (CPCC) with improved physio-mechanical properties; (2) incorporate metformin (CPCC-Met) to assess release; and (3) evaluate human dental pulp stem cells (hDPSCs) response.
View Article and Find Full Text PDFCase report: Illustrating associated malignancies in Paget's disease using contrast-enhanced mammography.
Front Oncol
January 2025
Breast Imaging Division, European Institute of Oncology (IEO), Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Milan, Italy.
Introduction: The following presentation explores the diagnostic potential of Contrast-Enhanced Mammography (CEM) in evaluating and managing Paget's Disease (PD) of the breast, particularly as an alternative or complementary tool to Magnetic Resonance Imaging (MRI) in cases where MRI is contraindicated or inconclusive.
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Current developments in robotic assistance technology for total knee arthroplasty: a comprehensive overview.
J Orthop Surg Res
January 2025
Department of Orthopedic, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China.
Knee arthritis is a common degenerative joint disease, usually with joint swelling, chronic pain, and dysfunction as the main clinical manifestations. At present, the conservative treatment for knee arthritis is mostly using anti-inflammatory and analgesic drugs, but the effect is mostly temporary, and can not prevent its progress and surgery is usually the last treatment method. Total knee arthroplasty, also known as TKA, is one of the most effective treatments for osteoarthritis of the knee that has progressed to the end stage.
View Article and Find Full Text PDFCost-effective adaptations increase rice production while reducing pollution under climate change.
Nat Food
January 2025
College of Environmental and Resource Sciences, Zhejiang University, Hangzhou, China.
Rice is a major source of greenhouse gas (GHG) and nitrogen pollution. While best management practices have been developed to enhance the sustainability of rice production under current climates, their adaptability and efficacy under future climate scenarios remain uncertain. Here we evaluated 49 best management practices across global grid cells of rice-producing areas in terms of increasing rice production, reducing GHG emissions and minimizing nitrogen pollution under future climate conditions.
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