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| http://dx.doi.org/10.1177/2050640619864879 | DOI Listing |
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Alkaloids solenopsins from fire ants display and activity against the yeast .
Virulence
December 2024
Universidade Federal do Rio de Janeiro, Instituto de Microbiologia Paulo de Góes, Departamento de Microbiologia Geral, Rio de Janeiro, Brazil.
The urgency surrounding as a public health threat is highlighted by both the Center for Disease Control (CDC) and World Health Organization (WHO) that categorized this species as a priority fungal pathogen. Given the current limitations of antifungal therapy for , particularly due to its multiple resistance to the current antifungals, the identification of new drugs is of paramount importance. Some alkaloids abundant in the venom of the red invasive fire ant (), known as solenopsins, have garnered attention as potent inhibitors of bacterial biofilms, and there are no studies demonstrating such effects against fungal pathogens.
View Article and Find Full Text PDFGuideline for the assessment and management of gastrointestinal symptoms following colorectal surgery-A UEG/ESCP/EAES/ESPCG/ESPEN/ESNM/ESSO collaboration. Part II-Good practice guidance | sequelae to benign diseases.
United European Gastroenterol J
October 2024
Department of Surgery, Maastricht University (Maastricht University, including Maastricht UMC+), Maastricht, The Netherlands.
What are the 100 most cited fungal genera?
Stud Mycol
July 2024
Westerdijk Fungal Biodiversity Institute, Uppsalalaan 8, Utrecht, 3584 CT, The Netherlands.
Article Synopsis
- * A bibliometric analysis was conducted to identify the top 100 most cited fungal genera, examining why some have more influence on mycology than others.
- * The paper discusses case studies for these top genera, providing insights into their ecology, economic impact, and key scientific advancements, while also outlining the historical context of research on these fungi.
Isolated and mixed effects of pure and formulated abamectin and difenoconazole on biochemical biomarkers of the gills of Danio rerio.
Aquat Toxicol
August 2024
NEEA/CRHEA/SHS, School of Engineering of São Carlos, Av. Trabalhador São Carlense, 400, 13.560-970 São Carlos, Brazil.
Pesticides are released into the environment daily, and their effects on nontarget species in aquatic ecosystems have been widely reported. To evaluate the adverse effects caused in adults of Danio rerio species exposed to the pesticides abamectin, difenoconazole, and their commercial formulations (Kraft 36EC® and Score 250EC®), both isolated and in mixtures, biochemical biomarkers were analyzed in the gills of organisms exposed to sublethal concentrations. To this end, the activities of the enzymes 7-ethoxyresorufin-O-deethylase (EROD), glucuronosyltransferase (UDPGT), glutathione-S-transferase (GST), catalase (CAT), glutathione peroxidase (GPx), glutathione reductase (GR), lipid hydroperoxide (LH), and malondialdehyde (MDA), which are indicative of oxidative stress, were measured after 48 h of exposure to the different pesticide treatments.
View Article and Find Full Text PDFRevisiting Biginelli-like reactions: solvent effects, mechanisms, biological applications and correction of several literature reports.
Org Biomol Chem
May 2024
University of Brasilia, Institute of Chemistry, Laboratory of Medicinal and Technological Chemistry. Campus Universitário Darcy Ribeiro, Brasília, DF, 70910-900, Brazil.
This study critically reevaluates reported Biginelli-like reactions using a Kamlet-Abboud-Taft-based solvent effect model. Surprisingly, structural misassignments were discovered in certain multicomponent reactions, leading to the identification of pseudo three-component derivatives instead of the expected MCR adducts. Attempts to replicate literature conditions failed, prompting reconsideration of the described MCRs and proposed mechanisms.
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