A short cut review of the literature was carried out to establish whether topical phenylephrine was an effective treatment for non-traumatic epistaxis. A single paper looked at this modality comparing it to another topical treatment. The author, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses are tabulated. It is concluded that further more robust studies are needed to answer this question.
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Article Synopsis
- Chemotherapy-induced alopecia can negatively affect patients' mental health, and this study explores using Phenylephrine, a topical vasoconstrictor, to potentially reduce hair loss during chemotherapy.
- The research focused on improving the skin permeation and sustained release of Phenylephrine using different lipid vesicles (ethosomes, invasomes, transfersomes) incorporated into hydrogels.
- Findings revealed that ethosomal and invasomal gels significantly improved drug delivery efficiency when compared to traditional gels, indicating their potential effectiveness in targeting local vasculature for sustained vasoconstriction.
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