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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7055663 | PMC |
| http://dx.doi.org/10.1373/clinchem.2019.307686 | DOI Listing |
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Dysregulation of plasma circulating microRNAs in all-cause and cause-specific cancers: the Rotterdam Study.
Biomark Res
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Department of Epidemiology, Erasmus MC, University Medical Center, P.O. Box 2040, Rotterdam, 3000 CA, The Netherlands.
MicroRNAs (miRNAs) are small non-coding RNAs involved in post-transcriptional regulation of gene expression. Mounting evidence underscores the dysregulation of miRNAs to be associated with cancer development and progression by acting as tumour suppressors and oncogenes. However, their potential as biomarkers for early diagnosis of different cancers remains incompletely unraveled.
View Article and Find Full Text PDFBioinformatics and Expression Analyses of miR-639, miR-641, miR-1915-3p and miR-3613-3p in Colorectal Cancer Pathogenesis.
J Cancer
July 2023
Department of General Surgery, Faculty of Medicine, Gaziantep University, 27310, Gaziantep, Turkey.
MicroRNAs (miRNAs) have important function in cancer development and progression. This study aims to determine the expression levels of miR-639, miR-641, miR-1915-3p, and miR-3613-3p in tissues of colorectal cancer (CRC) patients and the role of these miRNAs in the CRC pathogenesis. Tumor and non-tumor tissues were collected from a total of 59 CRC patients.
View Article and Find Full Text PDFIn silico Identification of Hypoxic Signature followed by reverse transcription-quantitative PCR Validation in Cancer Cell Lines.
Iran Biomed J
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Department of Molecular Virology, Pasteur Institute of Iran, Tehran, Iran.
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Predictive value of an exosomal microRNA-based signature for tumor immunity in cervical cancer patients treated with chemoradiotherapy.
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Department of Radiology, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, 060-8543, Japan.
Resistance of cervical cancer to radiotherapy with concurrent chemotherapy (CCRT) results in a poor prognosis. To identify new biomarkers for predicting the treatment response and prognosis, we explored exosomal microRNA (miRNA) expression signatures associated with the outcome of cervical cancer patients treated with CCRT. Exosomes were isolated from the plasma of 45 patients prior to CCRT during 2014-2020, and miRNA analysis was performed by next-generation sequencing.
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