The patient reported here, along with collective observations in the literature, suggest that deletion does not cause neutropenia. Potential therapeutic genome editing involving knockout of the mutant allele is therefore not expected to produce neutropenia.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712528 | PMC |
http://dx.doi.org/10.1182/bloodadvances.2019000498 | DOI Listing |
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!