The patient reported here, along with collective observations in the literature, suggest that deletion does not cause neutropenia. Potential therapeutic genome editing involving knockout of the mutant allele is therefore not expected to produce neutropenia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712528PMC
http://dx.doi.org/10.1182/bloodadvances.2019000498DOI Listing

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