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Knowledge and Awareness of Anaphylaxis and Anaphylactic Shock Among the General Population of the Western Region of Saudi Arabia.
Cureus
October 2024
Psychiatry, Mental Health Hospital, Ministry of Health, Jeddah, SAU.
Article Synopsis
- Anaphylactic shock is a serious condition triggered by allergens, but there is a general lack of awareness about its risks and management, particularly in the western region of Saudi Arabia.
- A survey conducted from January to June 2024 involved 501 participants, revealing that while many recognize the danger of anaphylaxis, knowledge about its symptoms and treatment options, such as epinephrine, is low.
- The results underscore the necessity for public awareness campaigns aimed at improving understanding and preparedness for anaphylactic emergencies.
School Teachers' Knowledge and Attitudes Related to Anaphylactic Reactions: A Cross-Sectional Study.
Cureus
October 2024
Nursing, King Abdullah Medical City, Makkah, SAU.
Introduction: Anaphylaxis is a severe allergic reaction marked by a sudden onset of symptoms affecting multiple bodily systems, and if not addressed promptly, it can lead to fatal outcomes. The primary clinical manifestations often involve skin rash, respiratory distress, and cardiovascular symptoms. Identifying these signs early is crucial for timely intervention, including the administration of epinephrine, aiming to prevent loss of life.
View Article and Find Full Text PDFGynostemma pentaphyllum saponins shield mice from peanut allergy by modulation of gut microbiota: A novel approach for peanut allergy management.
Phytomedicine
December 2024
State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau, China; Foshan Maternal and Child Health Research Institute, Foshan Women and Children's Hospital Affiliated to Southern Medical University, Foshan, China. Electronic address:
Background: Food allergies, particularly peanut (PN) allergies, are a growing concern, with fatal anaphylaxis incidents often reported. While palforzia is the sole FDA-approved drug for managing PN allergies, it is not universally effective.
Purpose: This study aimed to investigate the potential of Gynostemma pentaphyllum saponins (GpS) as a novel therapeutic agent for PN allergy through modulation of gut microbiota, addressing the limitations of current treatments.
Belimumab safety in adult and paediatric Chinese patients with systemic lupus erythematosus: A Phase 4, multicentre, observational study.
Lupus
December 2024
Pharmacovigilance, Medical Department, GSK, Shanghai, China.
Objective: Although belimumab has been widely used in patients with systemic lupus erythematosus (SLE) globally, real-world safety data among Chinese patients are limited, particularly for children. This study assessed the safety and tolerability of belimumab in adult and paediatric patients with SLE in China in real-world clinical practice.
Methods: This Phase 4, multicentre, prospective, observational study enrolled patients prescribed intravenous belimumab by their physicians in tertiary hospitals, independent of a clinical study, during routine clinical visits between May 2021 and May 2022.
A case report of fatal anaphylaxis on first exposure to rasburicase just before lymphoma treatment.
Allergy Asthma Clin Immunol
October 2024
Department of Hematology and Oncology, Japanese Red Cross Narita Hospital, Narita, Japan.
Article Synopsis
- * A case involving a 71-year-old woman with lymphoma resulted in fatal anaphylactic shock following her first dose of rasburicase, leading to multiple complications including heart compression and significant bleeding.
- * This case highlights that while it’s uncommon, rasburicase can cause deadly anaphylaxis even in patients who have not previously been exposed to the drug.
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