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Operationalizing goal setting as an outcome measure in trials involving patients with frailty, multimorbidity or complexity.
Contemp Clin Trials Commun
February 2025
Ageing and Movement Research Group, Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom.
Background/aims: In the absence of disease-modifying therapies for Parkinson's disease, much research focuses on improving quality of life, health and wellbeing. It is important to evaluate potential treatments and innovative care models in a robust and standardised way. Disease-specific outcomes have limitations in older people, those with cognitive impairment, multimorbidity, disability or short life expectancy.
View Article and Find Full Text PDFEarly circulating biomarkers to predict plasma leakage in dengue fever.
J Infect
January 2025
School of Biomedical Sciences, Faculty of Medicine, UNSW Sydney, NSW, 2052, Australia; Viral Immunology Systems Program, Kirby Institute, UNSW Sydney, NSW, 2052, Australia. Electronic address:
Background: Dengue, a mosquito-borne viral infection, poses a rapidly growing burden, particularly in low- and middle-income countries. Without early identification of patients at risk of severe outcomes (dengue haemorrhagic fever, severe dengue, and plasma leakage- the latter typically occurring on days 5-7 of illness), untriaged admissions lead to hospital overcrowding and suboptimal care.
Methods: This nested case-control study compared early-stage plasma samples (within the first 96hours of fever) from dengue patients with and without plasma leakage.
A novel concept of an acoustic ultrasound wearable for early detection of implant failure.
Sci Rep
December 2024
Center for Surgical Innovation and Engineering, Cedars Sinai Health System, Los Angeles, 90048, USA.
Mechanical failure of medical implants, especially in orthopedic poses a significant burden to the patients and healthcare system. The majority of the implant failures are diagnosed at very late stages and are of mechanical causes. This makes the diagnosis and screening of implant failure very challenging.
View Article and Find Full Text PDFPatient Experiences and Prerequisites of Collaboration as Partners in Person-Centred Care: An Interview Study.
Nurs Open
January 2025
Institute of Health and Care Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Aim: To explore what characterises communication and collaboration within a patient and professional partnership in outpatient care settings garnered from the experiences of persons living with long-term conditions.
Design: A qualitative descriptive study design.
Methods: Semi-structured individual interviews were conducted with 15 persons with long-term condition/s who experienced outpatient treatment or follow-up care.
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