Colorimetric and Fluorimetric DNA Detection with a Hydroxystyryl-Quinolizinium Photoacid and Its Application for Cell Imaging.

Chemistry

Department of Chemistry and Biology, and Center of Micro- and Nanochemistry and Engineering (Cμ), University of Siegen, Adolf-Reichwein-Str. 2, 57068, Siegen, Germany.

Published: October 2019

The combination of styryl dye properties with the acidity and strong photoacidity of the 2,2'-[(1''-hydroxy-4''-methyl-(E)-2'',6''-phenylene)]-bisquinolizinium enables the detection of DNA by distinct absorption and emission color changes and the fluorimetric detection of DNA in cells with epifluorescence and confocal fluorescence microscopy.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6790585PMC
http://dx.doi.org/10.1002/chem.201903017DOI Listing

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