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Purpose: Sleep (SL), physical activity (PA), and wellbeing (WB) are three factors linked to positive development in adolescence. Despite theoretical support and some empirical evidence of developmental associations between these factors, few studies have rigorously investigated reciprocal associations over time separating between-person and within-person effects, and none have investigated all three in concert. Thus, it remains unclear how the interplay between SL, PA and WB unfolds across time within individuals.

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Objective: This study aimed to investigate the longitudinal bi-directional relationship between self-reported restrictive eating behaviours and sleep characteristics within a sample of UK adolescents from the Millennium Cohort Study (MCS).

Method: Using a Structural Equation Modelling approach, the present study investigated the prospective associations between individual sleep behaviours (e.g.

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Purpose: Major depressive disorder is one of the most common and burdensome psychiatric disorders worldwide. This study evaluated the anxiolytic- and antidepressant-like activity of three semi-synthetic derivatives of xylopic acid (XA) to identify the most promising derivative based on mechanism(s) of action, in vivo pharmacokinetics and in vitro cytotoxicity.

Methods: The anxiolytic potential and the involvement of GABAergic mechanisms were assessed in the elevated plus-maze and open field tests in mice.

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New insights into freshwater ascomycetes: discovery of novel species in diverse aquatic habitats.

Front Cell Infect Microbiol

January 2025

Department of Economic Plants and Biotechnology, Yunnan Key Laboratory for Wild Plant Resources, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, Yunnan, China.

During investigations of freshwater fungi in Hunan and Yunnan provinces, China, sp. nov. (Nectriaceae), sp.

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Predicting the spatial and temporal responses of species exhibiting intraguild predation (IGP) relationships is difficult due to variation in potential interactions and environmental context. Eurasian badgers () are intraguild predators of European hedgehogs () and are implicated in their population decline via both direct predation and competition for shared food resources. Previous studies have shown spatial separation between these species and attributed this to hedgehogs experiencing a 'landscape of fear', but little is known about the potential role of differential habitat use.

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