Dinaciclib enhances NK-cell activity against leukemia cells in preclinical AML models. Enhanced NK-cell activation by dinaciclib-treated AML is associated with downregulation of inhibitory NK ligand HLA-E on leukemia cells.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712524 | PMC |
http://dx.doi.org/10.1182/bloodadvances.2019000064 | DOI Listing |
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