Lipid Droplets Grease Enterovirus Replication.

Cell Host Microbe

Division of Virology, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands. Electronic address:

Published: August 2019

Replication complexes of (+)RNA viruses of eukaryotes are associated with specialized membranous domains, termed replication organelles. How these structures develop is poorly understood. In a recent Cell paper, Laufman et al. (2019) reveal that enteroviruses recruit lipid droplets to support lipid synthesis required for the structural development of replication organelles.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9004532PMC
http://dx.doi.org/10.1016/j.chom.2019.07.017DOI Listing

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