AI Article Synopsis
- This study aims to compare two ultrasound techniques, HighMiB and LowMiR, for evaluating cerebral perfusion in patients with acute ischemic stroke caused by middle cerebral artery occlusion.
- Out of 31 patients, HighMiB was applicable for 16 and LowMiR for 8, with comparisons revealing that HighMiB detected hypoperfusion in more cortical areas than LowMiR, highlighting its diagnostic superiority.
- While LowMiR offers real-time imaging advantages, it falls short in imaging quality and semi-quantitative evaluation compared to HighMiB, suggesting a need for further consideration in clinical settings.
Article Abstract
Purpose: To prospectively evaluate the potential of semi-quantitative evaluation of cerebral perfusion in acute ischemic stroke by comparing two established ultrasound approaches.
Materials And Methods: Consecutive inclusion of patients with acute occlusion of middle cerebral artery (MCA) confirmed by either magnetic resonance imaging (MRI) or computed tomography (CT) perfusion imaging qualifying for interventional therapy. Comparison of bilateral high mechanical index (MI) bolus-kinetics (HighMiB) and unilateral low MI refill-kinetics (LowMiR) performed before specific treatment.
Results: In 16/31 patients HighMiB was eligible, in 8/31 patients LowMiR was eligible. In six out of these eight patients both HighMiB and LowMiR were eligible for direct comparison. In MR/CT perfusion imaging of the 16 patients eligible for HighMiB, 29/48 cortical regions of interest (ROIs) (60%) displayed hypoperfusion or ischemia, areas inadequately accessible by LowMiR. These ROIs made up 49% of the 59 ROIs displaying hypoperfusion or ischemia, altogether. Matching of parameters in normal and impaired ROIs between LowMiR and MRI/CT perfusion imaging was significantly poorer than in HighMiB.
Conclusion: LowMiR using refill-kinetics potentially has the advantage of real time imaging and better resolution. The diagnostic impact, however, proves inferior to HighMiB both with respect to imaging quality and semi-quantitative evaluation.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695115 | PMC |
| http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0220171 | PLOS |
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