Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664332 | PMC |
| http://dx.doi.org/10.17294/2330-0698.1637 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Robust discrimination between closely related species of salmon based on DNA fragments.
Anal Bioanal Chem
January 2025
Statistical Engineering Division, National Institute of Standards and Technology, 100 Bureau Drive, Gaithersburg, MD, 20899-8980, USA.
Closely related species of Salmonidae, including Pacific and Atlantic salmon, can be distinguished from one another based on nucleotide sequences from the cytochrome c oxidase sub-unit 1 mitochondrial gene (COI), using ensembles of fragments aligned to genetic barcodes that serve as digital proxies for the relevant species. This is accomplished by exploiting both the nucleotide sequences and their quality scores recorded in a FASTQ file obtained via Next Generation (NextGen) Sequencing of mitochondrial DNA extracted from Coho salmon caught with hook and line in the Gulf of Alaska. The alignment is done using MUSCLE (Muscle 5.
View Article and Find Full Text PDFCosts analysis of integrating group interpersonal therapy into HIV care services in Senegal.
Int J Ment Health Syst
January 2025
University of Bordeaux, National Institute for Health and Medical Research (INSERM) UMR 1219, Research Institute for Sustainable Development (IRD) EMR 271, Bordeaux Population Health Centre, Bordeaux, France.
Introduction: Group Interpersonal Therapy (IPT), an evidence-based treatment of depression recommended by the WHO mhGAP Intervention Guide, was implemented through a task-shifting approach in Senegal, as a treatment for depressed people living with HIV (PLWH). Since a description of the resources used and the implementation costs incurred is necessary to inform policymakers better, this study aimed to estimate the costs associated with its implementation.
Methods: Intervention costs were analyzed using an "ingredients-based costing approach" from the provider's perspective.
Estimation of factorial expressions and its improvement through calibration: A replication and extension of Tversky and Kahneman (1973).
Mem Cognit
January 2025
School of Interactive Computing, Georgia Institute of Technology, Atlanta, GA, USA.
Fifty years ago, Tversky and Kahneman (Cognitive Psychology, 5[2], 207-232, 1973) reported that people's speeded estimations of 8 × 7 × 6 × 5 × 4 × 3 × 2 × 1 were notably higher than their estimations for the equivalent expression in the opposite order, 1 × 2 × 3 × 4 × 5 × 6 × 7 × 8 (Median = 2,250 vs. 512, respectively). On top of this order effect, both groups grossly underestimated the correct value (40,320).
View Article and Find Full Text PDFSurvey and perspective on verification, validation, and uncertainty quantification of digital twins for precision medicine.
NPJ Digit Med
January 2025
Laboratory for Information and Decision Systems, Massachusetts Institute of Technology, Cambridge, MA, USA.
Digital twins in precision medicine provide tailored health recommendations by simulating patient-specific trajectories and interventions. We examine the critical role of Verification, Validation, and Uncertainty Quantification (VVUQ) for digital twins in ensuring safety and efficacy, with examples in cardiology and oncology. We highlight challenges and opportunities for developing personalized trial methodologies, validation metrics, and standardizing VVUQ processes.
View Article and Find Full Text PDFHybrid multi-objective optimization of µ-synthesis robust controller for frequency regulation in isolated microgrids.
Sci Rep
January 2025
Faculty of Engineering, Helwan University, Cairo, Egypt.
Frequency regulation in isolated microgrids is challenging due to system uncertainties and varying load demands. This study presents an optimal µ-synthesis robust control strategy that regulates microgrid frequency while enhancing system performance and stability-a proposed fixed-structure approach for selecting performance and robustness weights, informed by subsystem frequency analysis. The controller is optimized using multi-objective particle swarm optimization (MOPSO) and multi-objective genetic algorithm (MOGA) under inequality constraints, employing a Pareto front to identify optimal solutions.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!