In Praise of Remarkably Powerful Centamolecular Therapeutic Agents.

ACS Med Chem Lett

Department of Discovery Chemistry, Bristol-Myers Squibb Research and Development, PO Box 4000, Princeton, New Jersey 08543-4000, United States.

Published: August 2019

While biological medications have addressed many important and challenging therapeutic targets, the pharmacopeia is still dominated by centamolecules. In this Viewpoint, we illustrate the impact of centamolecule drugs on mortality and morbidity due to chronic viral infections and present select examples from other disease areas that highlight some of their remarkably powerful biochemical effects.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691479PMC
http://dx.doi.org/10.1021/acsmedchemlett.9b00286DOI Listing

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