A needle holder is one of the crucial surgical instruments for surgeons. Its prime function is to steadily hold the needle while applying sutures, thus avoiding injury to the surrounding tissues and to the surgeon's hand. Wide varieties of needle holders are available for use in orthopaedic practice. This review article briefly describes the biomechanics and other characteristics of some of the commonly used needle holders. The care aspects and wear features of needle holders are also discussed. A surgeon should be aware of the different types of needle holders, their special features, biomechanical properties, and specific uses as they are an important tool in the surgeon's armamentarium. (Journal of Surgical Orthopaedic Advances 28(2):89-96, 2019).
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Int J Pharm
December 2024
School of Pharmacy, Queen's University Belfast, Medical Biology Centre, 97 Lisburn Road, Belfast BT9 7BL, UK. Electronic address:
Hypertension is the most common pregnancy disorder and can lead to life-threatening conditions for both mother and fetus. However, managing this condition with oral and intravenous labetalol can be challenging, highlighting the need for alternative delivery methods. This study presents, for the first time, the development of novel powder-based reservoirs incorporated with hydrogel-forming microarray patches (MAPs) to facilitate the transdermal delivery of labetalol hydrochloride (HCl).
View Article and Find Full Text PDFHeart Rhythm
November 2024
Cardiovascular Division, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee. Electronic address:
Background: The utility of repeat ablation for premature ventricular contractions (PVCs) after prior ablation failure is not clear.
Objective: The purpose of this study was to assess the outcomes of repeat ablation and the use of different techniques in patients who failed prior PVC ablation.
Methods: We reviewed 239 consecutive patients who underwent PVC ablation.
Interv Pain Med
September 2024
Jordan Young Institute, Virginia Beach, VA, USA.
This series of FactFinders presents a brief summary of the evidence and outlines recommendations to minimize risks associated with cervical epidural injections. Evidence in support of the following facts is presented. - 1) CILESIs should be performed at C6-C7 or below, with C7-T1 as the preferred access point due to the more generous dorsal epidural space at this level compared to the more cephalad interlaminar segments.
View Article and Find Full Text PDFEndoscopy
December 2024
Department of Gastroenterology, Nippon Medical School, Graduate School of Medicine, Tokyo, Japan.
JBJS Essent Surg Tech
October 2024
Twin Cities Orthopedics, Minneapolis, Minnesota.
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