We conducted a single-center cross-sectional study to determine whether scrotal-testicular tissue oxygen saturation (S-T StO) measured by finger-mounted near-infrared spectroscopy is useful for the evaluation of testicular function. S-T StO was significantly higher in patients with nonobstructive azoospermia (NOA, p< 0.05), and showed a positive correlation with luteinizing hormone levels (LH) even in participants without NOA (r = 0.34, p< 0.05), suggesting that elevated S-T StO is associated with a reduction in testicular function.
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