Cardioneuroablation for neurocardiogenic syncope.

Heart Rhythm

São Paulo University, São Paulo Heart Hospital, and São Paulo Dante Pazzanese Cardiology Institute, São Paulo, Brazil. Electronic address:

Published: October 2019

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http://dx.doi.org/10.1016/j.hrthm.2019.08.008DOI Listing

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Introduction: Cardioneuroablation (CNA) has proven effectiveness in addressing hypervagotonia symptoms, such as neurocardiogenic syncope.

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Ganglionated plexi ablation in the right atrium for the treatment of cardioinhibitory syncope.

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Neurocardiogenic syncope, also called vasovagal syncope, represents one of the clinical manifestations of neurally mediated syncopal syndrome. Generally, the prognosis of the cardioinhibitory form of neurocardiogenic syncope is good, but quality of life is seriously compromised in patients who experience severe forms. Drug therapy has not achieved good clinical results and very heterogeneous data come from studies regarding permanent cardiac pacing.

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Background: As the most common cause of syncope, vasovagal syncope (VVS) is mediated by parasympathetic overactivity and/or sympathetic withdrawal. Although catheter ablation of ganglionated plexi or cardioneuroablation has been used to treat VVS, its role in quality of life (QoL) has not been formally evaluated. The aim of this study was to demonstrate if this novel treatment results in improvement QoL of patients with VVS.

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