O-specific polysaccharide and lipid A were obtained from the lipopolysaccharide from new strain of Рantoea agglomerans P1a by mild acid hydrolysis. It was found that the major form of lipid A presented by tetraacylated derivative containing biphosphorylated GlcN disaccharide, three 14:0 (3-OH) and 12:0 residues. The structure of the O-specific polysaccharide was established by chemical, NMR and computational methods: →3)-α-D-Manp-(1 → 4)-β-D-Fucp-(1 → 4)-ɑ-D-Fucp-(1→The LPS of Р. agglomerans P1a showed low level of toxicity and pyrogenicity to compare with LPS of E. coli O55:B5 and pyrogenal (respectively).
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.carres.2019.107767 | DOI Listing |
Publication Analysis
Top Keywords
agglomerans p1a
12
o-specific polysaccharide
12
structure o-specific
8
polysaccharide lipid
8
pantoea agglomerans
4
p1a lipopolysaccharide
4
lipopolysaccharide structure
4
lipid biological
4
biological activity
4
activity o-specific
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!