Objectives: This feasibility study aimed to assess the acceptability of inspiratory muscle training (IMT) in people with chronic obstructive pulmonary disease (COPD) who declined pulmonary rehabilitation (PR) as a potential treatment option or precursor to PR. Objectives were to assess attitudes to IMT, PR and alternatives to PR; factors influencing adherence with IMT and acceptability of outcome measures, research tools and study protocol.
Design: A pragmatic, mixed methods, prepost feasibility study was conducted. Recruitment took place over a 4-month period. Participants were followed up for a period of 6 months.
Settings: IMT sessions and assessments were conducted in the domiciliary setting.
Participants: Inclusion criteria: people over the age of 35, stable COPD, Medical Research Council Dyspnoea scale of 3 or above, declined PR.
Exclusion Criteria: history of spontaneous pneumothorax, incomplete recovery from a traumatic pneumothorax, asthma, known recently perforated eardrum, unstable angina, ventricular dysrhythmias, cerebrovascular event or myocardial infarction within the last 2 months. Participants were selected from a purposive sample. Of the 22 potential participants screened, 11 were recruited and interviewed. Ten participants commenced IMT. Seven participants completed the follow-up assessment.
Intervention: Eight weeks of IMT twice a day, 5 days a week with visits once weekly by a physiotherapist. Unsupervised IMT twice a day three times a week until follow-up at 6 months.
Outcomes: Acceptability of IMT and the study process was explored via semi-structured interviews. Adherence with IMT was assessed by the Powerbreathe K3 device and participant diaries. Uptake of PR was identified.
Results: IMT was found to be acceptable. Adherence was explored. Four people went on to participate in PR.
Conclusions: Feasibility was established. A randomised controlled trial is warranted to establish efficacy and cost-effectiveness of IMT in those who decline PR and IMT as an intervention to promote uptake of PR.
Trial Registration Number: NCT01956565; Post-results.
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http://dx.doi.org/10.1136/bmjopen-2018-028507 | DOI Listing |
Ups J Med Sci
January 2025
Centre for Clinical Research, Uppsala University, Västmanland County Hospital, Västerås, Sweden.
Background: Growth differentiation factor 15 (GDF-15) is a robust prognostic biomarker in patients with cardiovascular (CV) disease, and a better understanding of its clinical determinants is desirable. We aimed to study the associations between GDF-15 levels and in outpatients with peripheral arterial disease (PAD).
Methods: An explorative cross-sectional study (Study of Atherosclerosis in Vastmanland, Västerås, Sweden) included 439 outpatients with carotid or lower extremity PAD.
Water Res
December 2024
Institute for Advanced Membrane Technology (IAMT), Karlsruhe Institute of Technology (KIT), Hermann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen, Germany. Electronic address:
In flow-through reactors, the photodegradation rate can be improved by enhancing contact and increasing the photocatalyst loading. Both can be attained with a higher surface-to-volume ratio. While previous studies focused on thin membranes (30 - 130 µm) with small pore sizes of 20 - 650 nm, this work employed poly(tetrafluoroethylene) (PTFE) supports, of which pore sizes are in the order of 10 µm, while the porosities and thicknesses are variable (22.
View Article and Find Full Text PDFNeural Netw
December 2024
The State Key Laboratory of Information Engineering in Surveying, Mapping and Remote Sensing, Wuhan University, 129 Luoyu Road, Wuhan, 430079, China. Electronic address:
Modifying the structure of an existing network is a common method to further improve the performance of the network. However, modifying some layers in network often results in pre-trained weight mismatch, and fine-tune process is time-consuming and resource-inefficient. To address this issue, we propose a novel technique called Identity Model Transformation (IMT), which keep the output before and after transformation in an equal form by rigorous algebraic transformations.
View Article and Find Full Text PDFHigh Blood Press Cardiovasc Prev
January 2025
Institute of Sport Medicine and Science, National Italian Olympic Committee, Largo Piero Gabrielli, 1, 00197, Rome, Italy.
Introduction: Carotid IMT is a recognized marker for early atherosclerotic changes and a predictor of future CV events. Previous studies showed 11% increased risk of myocardial infarction with each 0.1 mm incremental increase of carotid IMT.
View Article and Find Full Text PDFNPJ Parkinsons Dis
January 2025
Department of Neurology, Beau Soleil Clinic, Montpellier, France.
Data on gait parameters during real-life activities and home rehabilitation programs for Persons with Parkinson's disease (PwPDs) are scarce. Although cueing has been shown to improve their gait in laboratory conditions, few studies have applied this technique in at-home rehabilitation programs. Our study aimed to explore the use of a real-time synchronized beat-step music program for at-home rehabilitation.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!