(group B streptococcus or GBS) is the most common cause of bacterial meningitis in infants, but is rarely the cause in adults. Across all non-pregnant adults it comprises 7% of bacterial meningitis cases, with a mortality rate of 56% in the elderly. Therefore, while rare, GBS should be a part of a patient's differential when initiating antibiotics in adults with chronic illnesses. We report a 78-year-old diabetic female admitted to the hospital with suspected meningitis. Lumbar puncture revealed grossly purulent cerebrospinal fluid (CSF) and she was started on antibiotics for empiric treatment of expected Thirty-one hours post-sampling, the CSF culture results returned positive for beta haemolytic GBS and treatment was altered accordingly. The case was complicated by concomitant periodic lateralising epileptiform discharges which were treated simultaneously. After 14 days of hospitalisation, the patient was discharged to a skilled nursing facility for further recovery.
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http://dx.doi.org/10.1136/bcr-2018-228040 | DOI Listing |
Am J Forensic Med Pathol
January 2025
County of Santa Clara, Medical Examiner-Coroner Office, San Jose, CA.
There are few reports that discuss the nebulous entity known as posttraumatic subacute meningitis. Herein, we describe a case where a male was found deceased with Streptococcus pyogenes meningitis 7 days after experiencing head trauma inflicted with a tow chain. Computed tomography scan prior to death revealed a scalp laceration with subcutaneous gas and a subdural hematoma.
View Article and Find Full Text PDFJ Oral Microbiol
January 2025
Periodontal Research Group, Department of Dentistry, School of Health Sciences, College of Medicine and Health, University of Birmingham, Edgbaston, UK.
Background: is a commensal bacterium and an early biofilm coloniser found in the human oral cavity. One of the biofilm matrix constituents is bacterial extracellular DNA (eDNA). Neutrophils are innate immune cells that respond to biofilms, employing antimicrobial mechanisms such as neutrophil extracellular trap (NET) and reactive oxygen species (ROS) release.
View Article and Find Full Text PDFFront Immunol
January 2025
Faculty of Biosciences and Aquaculture, Nord University, Bodø, Norway.
is a major causative agent of streptococcosis in Nile tilapia () and understanding its etiology is important to ensure the sustainable development of global tilapia farming. Our research group recently observed contrasting disease patterns in animals infected with two different serotypes (Ib and III). To better understand the basis for these divergent responses, we analyzed the brain transcriptome of Nile tilapia following bacterial exposure.
View Article and Find Full Text PDFInt J Clin Pediatr Dent
December 2024
Department of Pedodontics, Mamata Dental College, Khammam, Telangana, India.
Aim And Background: To evaluate and compare the efficiency of a manual, electrical, and chewable toothbrush for plaque removal in children.
Materials And Methods: A total of 58 children aged 8-14 years who reported to the Department of Pedodontics. The children and guardians were familiarized with the disclosing agent, manual toothbrush, electrical toothbrush, and chewable toothbrush before the commencement of the study with the help of video and verbal demonstrations.
Objective: Periorbital necrotizing soft tissue infection (NSTI) is a rare entity caused either by polymicrobial infection (type 1) or Streptococcus pyogenes and/or Staphylococcus species (type 2). A high level of clinical suspicion is necessary to make the diagnosis. We present 3 cases of NSTI illustrating our diagnostic and therapeutic approach.
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