In this paper, we propose a machine learning-based virtual physical therapist (PT) system to enable personalized remote training for patients with Parkinson's disease (PD). Three physical therapy tasks with multiple difficulty levels are selected to help patients with PD improve balance and mobility. Patients' movements are captured by a Kinect sensor. Criteria for each task are carefully designed by our PT co-author such that the patient's performance can be evaluated in an automated manner. Given the patient's motion data, we propose a two-phase human action understanding algorithm TPHAU to understand the patient's movements, and an error identification model to identify the patient's movement errors. To enable automated task recommendation, a machine learning-based model is trained from real patient and PT data to provide accurate, personalized, and timely task update recommendation for patients with PD, thereby emulating a real PT's behavior. Real patient data have been collected in the clinic to train the models. Experiments show that the proposed methods achieve high accuracy in patient action understanding, error identification and task recommendation. The proposed virtual PT system has the potential of enabling on-demand virtual care and significantly reducing cost for both patients and care providers.
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http://dx.doi.org/10.1109/TNSRE.2019.2934097 | DOI Listing |
Clin Toxicol (Phila)
January 2025
Department of Emergency Medicine, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.
Introduction: Delayed neurological sequelae is a common complication following carbon monoxide poisoning, which significantly affects the quality of life of patients with the condition. We aimed to develop a machine learning-based prediction model to predict the frequency of delayed neurological sequelae in patients with carbon monoxide poisoning.
Methods: A single-center retrospective analysis was conducted in an emergency department from January 01, 2018, to December 31, 2023.
BMJ Open
December 2024
Health Services and Systems Research, Duke-NUS Medical School, Singapore.
Introduction: As surgical accessibility improves, the incidence of postoperative complications is expected to rise. The implementation of a precise and objective risk stratification tool holds the potential to mitigate these complications by early identification of high-risk patients. Moreover, it could address the escalating costs from resource misallocation.
View Article and Find Full Text PDFAnal Chem
January 2025
Department of Cancer Biology and Molecular Medicine, Beckman Research Institute, City of Hope Comprehensive Cancer Center, Duarte, California 91010, United States.
Extracellular vesicles (EVs), membrane-encapsulated nanoparticles shed from all cells, are tightly involved in critical cellular functions. Moreover, EVs have recently emerged as exciting therapeutic modalities, delivery vectors, and biomarker sources. However, EVs are difficult to characterize, because they are typically small and heterogeneous in size, origin, and molecular content.
View Article and Find Full Text PDFJ Gen Intern Med
January 2025
Northwell, 2000 Marcus Ave., Suite 300, New Hyde Park, NY, 11042-1069, USA.
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