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A systematic review on the trend of transcriptomic study in livestock: An effort to unwind the complexity of adaptation in a climate change environment.
Heliyon
January 2025
Centre for Agricultural Genomics and Biotechnology, University of Debrecen, Debrecen, 4032, Hungary.
Heat stress has been proven to cause negative effects on livestock leading to lower productivity and economic value. Understanding how heat stress manifests within an animal's body is the first step in devising a heat stress mitigation strategy; transcriptomic studies are one of the methods used. Here, using a systematic literature review methodology, we examine the recent decade of transcriptomics' application to the study of livestock adaptation.
View Article and Find Full Text PDFExploring the Frontiers of Nanopore Sequencing in Food Safety and Food Microbiology.
Annu Rev Food Sci Technol
January 2025
1Food Science and Human Nutrition Department, University of Florida, Gainesville, Florida, USA; email:
Foodborne illnesses are a significant global public health challenge, with an estimated 600 million cases annually. Conventional food microbiology methods tend to be laborious and time consuming, pose difficulties in real-time utilization, and can display subpar accuracy or typing capabilities. With the recent advancements in third-generation sequencing and microbial omics, nanopore sequencing technology and its long-read sequencing capabilities have emerged as a promising platform.
View Article and Find Full Text PDFEvidence of Significant Intratumoral Transcriptomic Heterogeneity in Non-functioning Pituitary Adenomas Based on Location and Texture.
Cureus
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Neurological Surgery, Loyola University Medical Center, Maywood, USA.
Introduction Surgical resection remains a standard treatment of non-functioning pituitary adenomas (NFPA). These tumors have significant intratumoral variability of growth rates and texture hardness. This preliminary study aims to identify variations in gene expression of different locations and textures within the same tumor to better explain tumor pathophysiology.
View Article and Find Full Text PDFThe cardiac blood transcriptome predicts de novo onset of atrial fibrillation in heart failure.
J Mol Cell Cardiol Plus
June 2024
Nantes Université, CNRS, INSERM, l'institut du thorax, F-44000 Nantes, France.
Heart failure (HF) increases the risk of developing atrial fibrillation (AF), leading to increased morbidity and mortality. Therefore, better prediction of this risk may improve treatment strategies. Although several predictors based on clinical data have been developed, the establishment of a transcriptome-based predictor of AF incidence in HF has proven to be more problematic.
View Article and Find Full Text PDFTargeting a cysteine proteinase inhibitor and a defensin-like protein in Litchi chinensis seed development leveraging endosperm single-nucleus transcriptome.
Int J Biol Macromol
January 2025
Key Laboratory of Biology and Genetic Improvement of Horticultural Crops-South China/Guangdong Litchi Engineering Research Center, College of Horticulture, South China Agricultural University, Guangzhou, China. Electronic address:
Seed development is one of the most important agricultural traits, determining both the crop yield and quality of fleshy fruits. A typically abortive litchi cultivar, Guiwei, exhibits heterogeneity in seed size across production areas, years, and individual trees. Previous studies have shown that 'Guiwei' seed development failure is associated with endosperm arrest and chilling conditions.
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