AI Article Synopsis
- A new mechanical injector has been developed to improve the precision of delivering medication through syringes by using a sensitivity feature that detects tissue resistance.
- This injector automatically stops when it encounters softer tissue, ensuring accurate placement and consistent delivery of therapeutic liquids, especially in difficult injection areas like the eye.
- Its versatile design allows for adaptation in various medical settings, making it suitable for different injection types, including epidural, subcutaneous, and intraperitoneal access.
Article Abstract
The precision of the delivery of therapeutics to the desired injection site by syringes and hollow needles typically depends on the operator. Here, we introduce a highly sensitive, completely mechanical and cost-effective injector for targeting tissue reliably and precisely. As the operator pushes the syringe plunger, the injector senses the loss-of-resistance on encountering a softer tissue or a cavity, stops advancing the needle and delivers the payload. We demonstrate that the injector can reliably deliver liquids to the suprachoroidal space-a challenging injection site that provides access to the back of the eye-for a wide range of eye sizes, scleral thicknesses and intraocular pressures, and target sites relevant for epidural injections, subcutaneous injections and intraperitoneal access. The design of this simple and effective injector can be adapted for a broad variety of clinical applications.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688633 | PMC |
| http://dx.doi.org/10.1038/s41551-019-0350-2 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!