AI Article Synopsis
- About 200 million pre-school age children face developmental delays, influenced by various factors.
- A study conducted in Ceará, Brazil analyzed vitamin A supplementation's impact on child development, involving 1232 children aged 0-35 months.
- Results indicated that vitamin A supplementation benefits cognitive and motor development in well-nourished children, but stunted children did not experience any improvement, highlighting the need for both supplementation and better nutritional status.
Article Abstract
200 million pre-school age children are not developing properly. Delays in child development are associated with multiple factors. This study aims to analyze if vitamin A supplementation is associated with improved development and how this effect could be mediated by nutritional status. Population-based study surveyed a representative sample of 8000 households, 1232 children 0-35 months, in the state of Ceará, Brazil. The variables analysed included child developmental status, nutritional determinants and confounding factors. The main effects and interactions were evaluated using Cox regressive models. Vitamin A supplementation showed protective effect to delay in cognitive and motor development modified by interaction with nutritional status. While well-nourished supplemented children presented a 67% lower risk of cognitive delay (adjusted PRR = 0·33 [0·21-0·53]), stunted children had no benefit from supplementation (adjusted PRR = 0·97 [0·39-2·40]). Vitamin A supplementation has a protective effect on child development, but not in stunted children. This suggests that supplementation is effective in promoting child development, especially if associated to a joint effort to improve the nutritional status of children, given the importance of this mediator.
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| http://dx.doi.org/10.1590/1413-81232018248.22242017 | DOI Listing |
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